Results 81 to 90 of about 1,645,101 (196)

Case Report Acanthosis Nigricans Associated with an Adrenocortical Tumor in a Pediatric Patient [PDF]

open access: yes, 2020
Malignant acanthosis nigricans (AN) is a rare paraneoplastic syndrome seen primarily in adults with an underlying diagnosis of gastrointestinal adenocarcinoma.
N Demura   +9 more
core  

Adrenocortical tumors in children

open access: yesBrazilian Journal of Medical and Biological Research, 2000
Childhood adrenocortical tumors (ACT) are rare. In the USA, only about 25 new cases occur each year. In Southern Brazil, however, approximately 10 times that many cases are diagnosed each year.
R.C. Ribeiro   +7 more
doaj   +1 more source

Peripheral precocious puberty in Li–Fraumeni syndrome: a case report and literature review of pure androgen-secreting adrenocortical tumors

open access: yesJournal of Medical Case Reports, 2023
Introduction Pure androgen-secreting adrenocortical tumors are a rare but important cause of peripheral precocious puberty. Case presentation Here, we report a pure androgen-secreting adrenocortical tumor in a 2.5-year-old boy presenting with penile ...
Sofie Ryckx   +13 more
doaj   +1 more source

Inflammation-based score in pediatric adrenocortical carcinoma [PDF]

open access: yes
\ua9 2025 the author(s)Inflammation-based scores have been demonstrated to be independent prognostic factors in predicting outcomes in adult adrenocortical carcinoma (ACC).
Kutluk T   +28 more
core   +5 more sources

Omics Biomarkers in Precision Oncology: From the Lens of the ASCPT Biomarkers and Translational Tools and Oncology Communities

open access: yesClinical and Translational Science, Volume 19, Issue 8, August 2026.
ABSTRACT Omics biomarkers comprise several molecular entities, including genomic, epigenomic, transcriptomic, proteomic, and metabolomic signatures. They play an essential role in oncology drug development and clinical settings by enabling personalized medicine.
Mai Mehanna   +8 more
wiley   +1 more source

Hypercortisolism: Causes, Consequences and Clinical Significance – A Review of Pathophysiology

open access: yesDiabetes, Obesity and Metabolism, Volume 28, Issue S4, Page 3-16, August 2026.
ABSTRACT Hypercortisolism or Cushing syndrome is a heterogeneous clinical spectrum caused by chronic glucocorticoid excess, ranging from exogenous Cushing syndrome to rare endogenous aetiologies and the increasingly recognised entity of mild autonomous cortisol secretion (MACS). Physiological cortisol production is tightly regulated by the hypothalamic–
Mohamed Eldib   +3 more
wiley   +1 more source

Recent Advances in Genetic Testing and Clinical Management of Hereditary Breast and Ovarian Cancer (HBOC) in India

open access: yesCancer Medicine, Volume 15, Issue 7, July 2026.
A multidisciplinary approach to hereditary breast and ovarian cancer (HBOC) involving genetic testing, counseling, and targeted therapy enables effective risk reduction and personalized disease management. ABSTRACT Background Hereditary breast and ovarian cancer (HBOC) syndromes, responsible for 5%–10% of all breast and ovarian cancers in the general ...
Prathika Sherigar   +4 more
wiley   +1 more source

Adrenal Primary Ganglioneuroblastoma Presenting in Adulthood: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Ganglioneuroblastoma is a rare neuroblastic tumor derived from embryonic neural crest cells, composed of mature gangliocytes and immature neuroblasts. Although most neuroblastic tumors present in children and commonly involve the adrenal glands, adrenal ganglioneuroblastoma is rare in adults, with only 25 previously reported cases.
Keiichiro Yasuda   +8 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

open access: yesThe FEBS Journal, Volume 293, Issue 13, Page 3991-4013, July 2026.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto   +9 more
wiley   +1 more source

Conditional ablation of RGS2 in myeloid cells does not influence blood pressure and organ damage in angiotensin II‐induced hypertension in mice

open access: yesPhysiological Reports, Volume 14, Issue 14, July 2026.
Abstract The role of the immune system in the development of hypertension is well‐established. Recent studies revealed the critical role of G‐protein‐coupled receptor signaling, particularly angiotensin II (Ang II) type 1 receptor (AT1R), in immune cell function.
Pablo Nakagawa   +14 more
wiley   +1 more source

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