Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: Summary statement of the growth hormone research society workshop on adult growth hormone deficiency [PDF]
Based on the increasing body of evidence that adults with GH deficiency (somatotropin deficiency) have impaired health that improves with GH replacement, many countries have already approved the use of GH for replacement therapy in adults with GH ...
Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency +1 more
core +1 more source
Harmonization of growth hormone measurements with different immunoassays by data adjustment [PDF]
Background: The aim of our study was to evaluate the between-assay variability of commercially available immunoassays for the measurement of human growth hormone (hGH).
Bidlingmaier, Martin +21 more
core +1 more source
A Recessive Mutation Resulting in a Disabling Amino Acid Substitution (T194R) in the LHX3 Homeodomain Causes Combined Pituitary Hormone Deficiency [PDF]
Background/Aims: Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system. We describe pediatric patients with combined pituitary hormone deficiency (CPHD)
Hiedl, Stefan +7 more
core +1 more source
Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation [PDF]
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox ...
Bird, A. +29 more
core +1 more source
An Approach to Traumatic Brain Injury-Related Hypopituitarism: Overcoming the Pediatric Challenges
Traumatic brain injury (TBI)-related hypopituitarism is a rare polymorphic complication of brain injury, with very little data, particularly concerning children and teenagers.
Raluca Maria Vlad +7 more
doaj +1 more source
Long-acting growth hormones: innovations in treatment and guidance on patient selection in pediatric growth hormone deficiency. [PDF]
Long-acting growth hormones (LAGHs) represent a significant advancement in the treatment of pediatric GH deficiency, offering an alternative to daily recombinant human GH (rhGH) therapy. Traditional rhGH treatments, although effective, require daily injections, often leading to poor adherence due to the frequency of dosing, injection pain, and ...
Rodaro C +3 more
europepmc +5 more sources
Causes of short stature in Iraqi hospital based study patients
Backgrounds: Growth is an important objective parameter of general health of the child. Normal growth requires adequate nutrition along with various hormonal stimuli. Short stature is a common cause of referral to pediatric endocrinologists.
Munib A. AlZubaidi +2 more
doaj +1 more source
Objectives. The standard of treatment for pediatric growth hormone deficiency (GHD) is daily subcutaneous recombinant human growth hormone (rhGH) injections. The efficacy of rhGH treatment given as daily intravenous (IV) boluses is not known.
Emir Tas +3 more
doaj +1 more source
Short stature is a common reason for a child to visit the endocrinologist, and can be a variant of normal or secondary to an underlying pathologic cause. Pathologic causes include growth hormone deficiency (GHD), which can be congenital or acquired later.
Colleen O\u27Neill +3 more
core +1 more source
Cost-effectiveness of somatrogon in the Spanish pediatric population with growth hormone deficiency
To analyze the cost-effectiveness of weekly somatrogon compared to daily growth hormones (GH-d) in the pediatric population of Spain with growth hormone deficiency (GHD).Markov model with two states (patients with or without GH-d or somatrogon treatment) in prepubertal children (3 to 11 years and 3 to 12 years in girls and boys, respectively) with GHD ...
Andreu Crespo, M.A. +6 more
openaire +4 more sources

