Results 31 to 40 of about 23,786 (267)

Clinical Features of Transient Growth Hormone Deficiency [PDF]

, 2023
Background: Most patients with idiopathic growth hormone deficiency (iGHD) in childhood have normal GH stimulation test results in adulthood. The present study aimed to investigate the characteristics and possible etiology of transient iGHD.
Kazuhiro Shimura, Kento Ikegawa, Yuki Sakai, Yukihiro Hasegawa   +3 more
core   +1 more source

The effects of recombinant human growth hormone therapy on thyroid function in pediatric patients with growth hormone deficiency [PDF]

Translational Pediatrics, 2021
Recombinant human growth hormone (rhGH) was approved for the therapy of pediatric patients with growth hormone deficiency (GHD) by the Food and Drug Administration (FDA) of the United States in 1985. This study aims to evaluate the effects of rhGH therapy on thyroid function in pediatric patients with GHD.A total of 55 pediatric patients, who had been ...
Yao, Qian, Zheng, Dong, Liang, Yan, Hou, Ling, Ying, Yan-Qin, Luo, Xiao-Ping, Wu, Wei   +6 more
openaire   +2 more sources

What do we do now that the long-acting growth hormone is here?

Frontiers in Endocrinology, 2022
In standard 52-week phase III clinical trials, once weekly lonapegsomatropin, somatrogon and somapacitan have been found to yield non-inferior height velocities and similar safety profiles to daily GH (DGH) in children with pediatric growth hormone ...
Bradley S. Miller
doaj   +1 more source

Should Pediatric Endocrinologists Consider More Carefully When to Perform a Stimulation Test?

Frontiers in Endocrinology, 2021
IntroductionPediatric endocrinology rely greatly on hormone stimulation tests which demand time, money and effort. The knowledge of the pattern of pediatric endocrinology stimulation tests is therefore crucial to optimize resources and guide public ...
Arturo Penco, Benedetta Bossini, Manuela Giangreco, Viviana Vidonis, Giada Vittori, Nicoletta Grassi, Maria Chiara Pellegrin, Elena Faleschini, Egidio Barbi, Egidio Barbi, Gianluca Tornese   +10 more
doaj   +1 more source

Harmonization of growth hormone measurements with different immunoassays by data adjustment [PDF]

, 2011
Background: The aim of our study was to evaluate the between-assay variability of commercially available immunoassays for the measurement of human growth hormone (hGH).
Bidlingmaier, Martin, Oliver Blankenstein, Jürgen Kratzsch, Körner, Antje, Wieland Kiess, Anne Müller, Markus Scholz, Antje Körner, Thiery, Joachim, Martin Bidlingmaier, Müller, Anne, Scholz, Markus, Blankenstein, Oliver, Annegret Heider, Roland Pfäffle, Joachim Thiery, Heider, Annegret, Kratzsch, Jürgen, Gerhard Binder, Pfäffle, Roland, Binder, Gerhard, Kiess, Wieland   +21 more
core   +1 more source

An Approach to Traumatic Brain Injury-Related Hypopituitarism: Overcoming the Pediatric Challenges

Diagnostics, 2023
Traumatic brain injury (TBI)-related hypopituitarism is a rare polymorphic complication of brain injury, with very little data, particularly concerning children and teenagers.
Raluca Maria Vlad, Alice Ioana Albu, Irina Delia Nicolaescu, Ruxandra Dobritoiu, Mara Carsote, Florica Sandru, Dragos Albu, Daniela Păcurar   +7 more
doaj   +1 more source

A Recessive Mutation Resulting in a Disabling Amino Acid Substitution (T194R) in the LHX3 Homeodomain Causes Combined Pituitary Hormone Deficiency [PDF]

, 2012
Background/Aims: Recessive mutations in the LHX3 homeodomain transcription factor gene are associated with developmental disorders affecting the pituitary and nervous system. We describe pediatric patients with combined pituitary hormone deficiency (CPHD)
Hiedl, Stefan, Duran-Prado, Mario, Lohse, Peter, Roeb, Julia, Rhodes, Simon J., Malik, Raleigh E., Bechtold-Dalla Pozza, Susanne, Park, Soyoung   +7 more
core   +1 more source

Recombinant human growth hormone for the treatment of growth disorders in children: a systematic review and economic evaluation [PDF]

, 2010
Study found that treatment with recombinant human growth hormone gave significantly greater benefits in stature for children with growth hormone deficiency (GHD), Turner syndrome, Prader–Willi syndrome, chronic renal insufficency, short stature homeobox ...
Bird, A., Baxter, L, Gospodarevskaya, E., K Welch, Cooper, Keith, L Baxter, Frampton, G. K., A Bird, Frampton, GK, Gospodarevskaya, Elena, Gospodarevskaya, E, Welch, K, Bryant, J, Takeda, A, Frampton, G.K., Cooper, K., GK Frampton, Takeda, Andrea, Bird, A, Bryant, J., J Bryant, K Cooper, Welch, Karen, Welch, K., Baxter, L., Takeda, A., Bryant, Jackie, A Takeda, E Gospodarevskaya, Cooper, K   +29 more
core   +1 more source

Prolyl Endopeptidase-like Deficiency Associated with Growth Hormone Deficiency [PDF]

, 2023
Prolyl endopeptidase-like (PREPL) deficiency (MIM#616224) is a rare congenital disorder characterised by neonatal hypotonia and feeding difficulties, growth hormone (GH) deficiency and hypergonadotropic hypogonadism.
Maria Irene Valenzuela, Laura Sayol-Torres, Maria Clemente, Rosangela Tomasini, Paula Fernández-Alvarez, Diego Yeste   +5 more
core   +1 more source

Treatment of Growth Hormone Deficiency via Daily Intravascular Injections in a Child with Bleeding Disorder

Case Reports in Endocrinology, 2021
Objectives. The standard of treatment for pediatric growth hormone deficiency (GHD) is daily subcutaneous recombinant human growth hormone (rhGH) injections. The efficacy of rhGH treatment given as daily intravenous (IV) boluses is not known.
Emir Tas, Serife E. Uzun, Vildan Tas, Juan D. Mejia-Otero   +3 more
doaj   +1 more source