Results 21 to 30 of about 23,786 (267)

Cost-effectiveness of somatrogon in the Spanish pediatric population with growth hormone deficiency [PDF]

Expert Review of Pharmacoeconomics & Outcomes Research, 2023
To analyze the cost-effectiveness of weekly somatrogon compared to daily growth hormones (GH-d) in the pediatric population of Spain with growth hormone deficiency (GHD).Markov model with two states (patients with or without GH-d or somatrogon treatment) in prepubertal children (3 to 11 years and 3 to 12 years in girls and boys, respectively) with GHD ...
Andreu Crespo, M.A., Castro-Feijóo, L., Labarta-Aizpún, J.I., Peral, C., Barrueta, J.A., Rubio-Rodríguez, D., Rubio-Terres, C.   +6 more
openaire   +4 more sources

The economic burden of pediatric growth hormone deficiency in Italy: a cost of illness study. [PDF]

J Endocrinol Invest
Abstract Purpose Growth hormone deficiency (GHD) is a rare condition with a worldwide prevalence of 1 patient in 4000 to 10,000 live births, placing a significant economic burden on healthcare systems. The aim of this study is to generate evidence on the economic burden of children and adolescents with GHD treated with ...
Cappa M, Pozzobon G, Orso M, Maghnie M, Patti G, Spandonaro F, Granato S, Novelli G, La Torre D, Salerno M, Polistena B.   +10 more
europepmc   +6 more sources

Treatment of Pediatric Growth Hormone Deficiency With Oral Secretagogues Revisited. [PDF]

J Endocr Soc, 2021
Yau M, Rapaport R.
europepmc   +3 more sources

The Rising Popularity of Growth Hormone Therapy and Ensuing Orthopedic Complications in the Pediatric Population: A Review [PDF]

Children
The utilization of recombinant human growth hormone therapy in pediatric populations, originally approved to treat diseases of growth hormone deficiency, has expanded to encompass a broader range of indications, leading to a threefold increase in its ...
Samuel Zverev, Zachary M. Tenner, Carlo Coladonato, Meredith Lazar-Antman   +3 more
doaj   +2 more sources

Patient-Centric Design of the Lonapegsomatropin Auto-Injector for Growth Hormone Deficiency: Usability Validation of Safe and Effective Use [PDF]

Medical Devices: Evidence and Research
Michael Lau,1 Paul Erik Fabricius,2 Nils Berg Madsen,3 Henrik Egesborg,3 Josephine Jensen3 1Human Factors Engineering, Insight by Nemera, Chicago, IL, USA; 2Industrial Design and HFE, Phillips-Medisize A/S, Struer, Denmark; 3Device Development, Ascendis ...
Lau M, Fabricius PE, Madsen NB, Egesborg H, Jensen J   +4 more
doaj   +2 more sources

Differential reversibility of anterior and posterior pituitary dysfunction in delayed recurrent pediatric Rathke’s cleft cyst [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Rathke’s cleft cyst (RCC) is a benign sellar or suprasellar lesion increasingly detected by magnetic resonance imaging (MRI). Although surgery is indicated for symptomatic or enlarging RCCs, recurrence may occur and reoperation may be required ...
Atsuko Ogasawara, Shozo Yamada, Go Matsuoka   +2 more
doaj   +2 more sources

Treatment of short stature and growth hormone deficiency in children with somatotropin (rDNA origin) [PDF]

Biologics: Targets & Therapy, 2008
Dana S HardinOhio State University and Columbus Children’s Hospital, Columbus, Ohio, USAAbstract: Somatotropin (growth hormone, GH) of recombinant DNA origin has provided a readily available and safe drug that has greatly improved management of
Dana S Hardin
doaj   +1 more source

Development of a Predictive Enrichment Marker for the Oral GH Secretagogue LUM-201 in Pediatric Growth Hormone Deficiency. [PDF]

J Endocr Soc, 2021
Bright GM, Do MT, McKew JC, Blum WF, Thorner MO.   +4 more
europepmc   +2 more sources

Economic burden of growth hormone deficiency in a US pediatric population [PDF]

Journal of Managed Care & Specialty Pharmacy, 2021
Abstract Pediatric GHD is a rare disorder of short stature that is currently treated with daily injections of GH. In addition to short stature, GHD is associated with other comorbidities such as impaired musculoskeletal development, cardiovascular disease, and decreased quality of life.
Kaplowitz, Paul B, Manjelievskaia, Janna, Lopez-Gonzalez, Lorena, Marrow, Cynthia D, Pitukcheewanont, Pisit, Smith, Alden   +5 more
openaire   +3 more sources

Growth Hormone Deficiency [PDF]

, 2022
Short stature is a common reason for a child to visit the endocrinologist, and can be a variant of normal or secondary to an underlying pathologic cause. Pathologic causes include growth hormone deficiency (GHD), which can be congenital or acquired later.
Colleen O\u27Neill, Mariam Gangat, Colleen O'Neill, Sally Radovick   +3 more
core   +1 more source