Treatment Adherence to Injectable Treatments in Pediatric Growth Hormone Deficiency Compared With Injectable Treatments in Other Chronic Pediatric Conditions: A Systematic Literature Review [PDF]
Frontiers in Endocrinology, 2022 BackgroundPediatric patients with growth hormone deficiency (GHD) are currently treated with daily injections of recombinant human growth hormone (rhGH) to promote linear growth and enable attainment of normal adult height.
Roy Gomez +6 more
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Delphi-based Spanish consensus on the use of long-acting growth hormone in pediatric growth hormone deficiency: recommendations from the ConverGHe Working Group [PDF]
Frontiers in EndocrinologyBackgroundLong-acting growth hormone (LAGH) formulations have emerged as an alternative to daily recombinant human growth hormone (rhGH) in pediatric growth hormone deficiency (GHD).
Lidia Castro-Feijóo +5 more
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Exploring Potentially Modifiable Factors That Influence Treatment Non-Adherence Amongst Pediatric Growth Hormone Deficiency: A Qualitative Study [PDF]
Patient Preference and Adherence, 2020 Selina Graham, Vivian Auyeung, John Weinman School of Cancer and Pharmaceutical Sciences, King’s College London, London, UKCorrespondence: Selina GrahamSchool of Cancer and Pharmaceutical Sciences, King’s College London, Franklin-Wilkins ...
Graham S, Auyeung V, Weinman J
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Skeletal Accrual in Pediatric Growth Hormone Deficiency: A Narrative Review [PDF]
Current Issues in Molecular BiologyGrowth hormone deficiency (GHD) is a frequent cause of impaired linear growth and may also affect skeletal development and bone mass acquisition. This narrative review summarizes the current evidence on bone health in pediatric GHD, with a focus on ...
Ignazio Cammisa +5 more
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Precision Dosing for Pediatric Growth Hormone Deficiency With Daily and Weekly Growth Hormone [PDF]
MedCommPediatric growth hormone deficiency (GHD) typically requires daily injections of recombinant human growth hormone (rhGH). Long‐acting PEGylated recombinant human growth hormone (PEG‐rhGH) formulations have been developed to reduce injection frequency and
Wei Wu +12 more
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Obesity-Related Changes in Growth Hormone Stimulation Test Performance Under Pediatric Growth Hormone Deficiency [PDF]
ChildrenBackground/Objectives: The objective of this study is to determine the extent to which obesity alters the diagnostic reliability of the clonidine stimulation test (CST) for growth hormone deficiency (GHD) and whether incorporating insulin-like growth ...
Semine Ozdemir Dilek +1 more
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Evidence map and gap analysis of metabolic change in pediatric growth hormone deficiency treated with growth hormone [PDF]
Pediatric InvestigationImportance Recombinant human growth hormone (rhGH) improves height in children with growth hormone deficiency (GHD). However, its metabolic effects remain unclear. Objective To synthesize evidence regarding the metabolic effects of rhGH or growth hormone
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Somatrogon in pediatric growth hormone deficiency: a comprehensive review of clinical trials and real-world considerations [PDF]
Annals of Pediatric Endocrinology & MetabolismGrowth hormone (GH) is crucial for childhood growth and body composition. In pediatric GH deficiency (pGHD), the pituitary gland fails to produce sufficient GH, which affects linear growth in childhood.
Aristides K. Maniatis +4 more
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Real-World Canadian Insights into Pediatric Growth Hormone Deficiency: Perspectives on Daily and Long-Acting Growth Hormone from Patients, Caregivers, and Healthcare Providers [PDF]
Patient Preference and AdherenceDavid Nguyen,1 Ufuk Coşkun,2 Chantal Cadieux,1 Jamie Harvey,3 Olga Moshkovich,2 Neha Durgam,2 M. Alex Bellenger,2 Vicky Turner,4 Duygu Alpan,2 Triza Brion21Pfizer, Kirkland, Quebec, Canada; 2ICON Clinical Research, Blue Bell, PA, USA; 3The ...
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Drug Design, Development and Therapy, 2022 Bradley S Miller,1 Kevin CJ Yuen2 1Pediatric Endocrinology, University of Minnesota Medical School, Minneapolis, MN, USA; 2Department of Neuroendocrinology and Neurology, Barrow Pituitary Center, University of Arizona College of Medicine and Creighton ...
Miller BS, Yuen KCJ
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