Results 181 to 190 of about 10,162 (212)

Establishment and application of a quadruple RT-qPCR method for simultaneous detection of porcine enteric coronaviruses. [PDF]

open access: yesFront Vet Sci
Ye C   +19 more
europepmc   +1 more source

Oral administration of coated PEDV-loaded microspheres elicited PEDV-specific immunity in weaned piglets

Vaccine, 2018
Porcine epidemic diarrhea virus (PEDV) infects pigs of all ages by invading villous epithelial cells of the small intestine causing severe diarrhea with high mortality rate in suckling piglets. Mucosal immunity is believed to play an important role in PEDV control and mucosal delivery of vaccines induces mucosal immunity more efficiently than ...
Zhichao Xu, Yongchang Cao
exaly   +3 more sources

Computationally-driven epitope identification of PEDV N-protein and its application in development of immunoassay for PEDV detection

Journal of Pharmaceutical and Biomedical Analysis, 2023
The nucleocapsid (N) protein is a suitable candidate for early diagnosis of porcine epidemic diarrhea virus (PEDV). Here, we identified the linear B-cell epitopes of the PEDV N-protein by integrating a computational-experimental framework and constructed three-dimensional (3D) structure model of the N protein using the ColabFold program in Google ...
Junzeng, Pang   +9 more
openaire   +3 more sources

Two novel porcine epidemic diarrhea virus (PEDV) recombinants from a natural recombinant and distinct subtypes of PEDV variants

open access: yesVirus Research, 2017
Porcine epidemic diarrhea virus (PEDV) causes devastating impact on global pig-breeding industry and current vaccines have become not effective against the circulating PEDV variants since 2011. During the up-to-date investigation of PEDV prevalence in Fujian China 2016, PEDV was identified in vaccinated pig farms suffering severe diarrhea while other ...
Nanhua Chen, Shuangjie Li, Shuai Li
exaly   +3 more sources

PEDV: Insights and Advances into Types, Function, Structure, and Receptor Recognition

open access: yesViruses, 2022
Porcine epidemic diarrhea virus (PEDV) has been endemic in most parts of the world since its emergence in the 1970s. It infects the small intestine and intestinal villous cells, spreads rapidly, and causes infectious intestinal disease characterized by vomiting, diarrhea, and dehydration, leading to high mortality in newborn piglets and causing massive
Huanyu Zhang, Yang yang
exaly   +4 more sources

The S protein of a novel recombinant PEDV strain promotes the infectivity and pathogenicity of PEDV in mid‐west China

Transboundary and Emerging Diseases, 2022
Porcine epidemic diarrhoea virus (PEDV) is an emerging and re-emerging swine enterovirus that causes highly contagious diarrhoea and mortality in piglets. To better understand the current prevalence of PEDV in mid-west China, and to find out the reason for the re-emergence of PEDV from the viral genomic characteristics.
Haixin Liu   +10 more
openaire   +2 more sources

PEDV Leader Sequence and Junction Sites

1995
The leader sequence of coronaviruses plays an important role in the replication of the coronaviruses. One model for the mRNA synthesis describes the leader as the primer which binds to the intergenic sequences (IS) on the negative copy of the genome.1 Recently it was reported that the leader sequence regulates the expression of the viral proteins ...
K, Tobler, M, Ackermann
openaire   +2 more sources

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