Results 31 to 40 of about 10,551,477 (298)

Peeling Plaids Apart: Context Counteracts Cross-Orientation Contrast Masking [PDF]

open access: yes, 2009
Background: Contrast discrimination for an image is usually harder if another image is superimposed on top. We asked whether such contrast masking may be enhanced or relieved depending on cues promoting integration of both images as a single pattern ...
Verghese, P.   +5 more
core   +2 more sources

Study on Peeling Performance of T-Type Brazing Joints Based on Energy Method

open access: yesMetals
Brazing technology is widely used in modern industrial systems as an important connection method. The brazing joints are the weakest zone in the whole structure and directly determine the working efficiency and life of the entire system.
Peng-Yang Duan   +2 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Activation of quiescent polypoidal choroidal vasculopathy after membrane peeling vitrectomy for epiretinal membrane: a case report

open access: yesBMC Ophthalmology, 2021
Background Regular membrane peeling vitrectomy for epiretinal membrane (ERM) patients seldom causes large pigment epithelial detachment (PED). We presented an unusual case of the activation of quiescent polypoidal choroidal vasculopathy (PCV) after ...
Yuelin Wang   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Porous Polyethylene Bundles with Enhanced Hydrophobicity and Pumping Oil-Recovery Ability via Skin-Peeling

open access: yes, 2018
Developing a feasible and efficient adsorption material for the large area of an oil leak is still challenging due to the critical limitation of complex production process and expensive cost.
Zhanhu Guo (1492291)   +9 more
core   +2 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Rational production of veneer by IR-heating of green wood during peeling: Modeling experiments [PDF]

open access: yes, 2012
Heating green wood logs by infrared (IR) radiation during peeling for veneer production has been numerically simulated, focusing on the heating kinetics of a green wood cylinder rotating with a decreasing radius.
OULD AHMEDOU, Sid' Ahmed   +4 more
core  

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