Results 41 to 50 of about 2,725,232 (305)
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Peer Review system: A Golden standard for publications process [PDF]
, 2018 Peer review process helps in evaluating and validating of research that is published in the journals. U.S. Office of Research Integrity reported that data fraudulence was found to be involved in 94% cases of misconduct from 228 identified articles ...
Lasker, Shamima Parvin
core
Cooperation & Liaison between Universities & Editors (CLUE): recommendations on best practice
Research Integrity and Peer Review, 2021 Background Inaccurate, false or incomplete research publications may mislead readers including researchers and decision-makers. It is therefore important that such problems are identified and rectified promptly.
Elizabeth Wager +2 more
doaj +1 more source
Modern Trends in Research Assessment: A Case of the Netherlands
Ekonomika Nauki, 2023 After the departure of commercial scientific information databases such as Scopus and Web of Science from Russia, the problem of building a new system for research assessment is more relevant than ever.
D. M. Kochetkov
doaj +1 more source
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
'Peer review of learning and teaching in higher education: international perspectives' by Judyth Sachs and Mitch Parsell : review [PDF]
, 2014 Book reviewThis collection of essays, edited by Judyth Sachs and Mitch Parsell, is focused on the research behind, and the practical application of, peer review in higher education.
Darwood, Nicola
core
Digital Chinese Medicine, 2018 : Objective Identification of one’s constitution based on a combination of features and back propagation neural network theory is needed in modern medicine and traditional Chinese medicine (TCM).
Yue Luo +3 more
doaj +1 more source
Aβ42 promotes the aggregation of α‐synuclein splice isoforms via heterogeneous nucleation
FEBS Letters, EarlyView.The aggregation of amyloid‐β (Aβ) and α‐synuclein (αSyn) is associated with Alzheimer's and Parkinson's diseases. This study reveals that Aβ aggregates serve as potent nucleation sites for the aggregation of αSyn and its splice isoforms, shedding light on the intricate interplay between these two pathogenic proteins.
Alexander Röntgen +2 more
wiley +1 more source
Peer review innovations in Humanities: how can scholars in A&H profit of the "wisdom of the crowds"? [PDF]
, 2010 Though supported by a large number of scholars in Scientific, Technical, and Medical (STM) disciplines traditional peer review does not live up to the needs of an efficient scholarly communication system and of quality research control.
Cassella, Maria
core
How to Peer Review for Scientific Journals?
International Journal of Advanced Medical and Health ResearchPeer review is the evaluation of scientific, academic, or professional work by experts in the field. This process starts when the editor of a peer-reviewed journal sends an article or a manuscript to two or more reviewers for review.
Mukta Wyawahare
doaj +1 more source