Results 71 to 80 of about 3,137,448 (307)
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Digital Chinese Medicine Research: an Overview
: Digital Chinese medicine (DCM) is an emerging interdisciplinary field developed from traditional Chinese medicine (TCM) and information science. In this article, we consider the significance and propose an architecture for DCM research, and highlight ...
Hui-Yong Huang, Jun-Feng Yan, Zhi-Xi Hu
doaj
Implementing a "publish, then review" model of publishing
From July 2021 eLife will only review manuscripts already published as preprints, and will focus its editorial process on producing public reviews to be posted alongside the preprints.
Michael B Eisen+5 more
doaj +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito+6 more
wiley +1 more source
Clashing Concepts and Methods: Assessing Excellence in the Humanities and Social Sciences
The humanities are going through a period of exceptional vitality characterised by the proliferation of novel interpretative frameworks, methodologies and perspectives.
Peter Scott
doaj +1 more source
Peer influences on college drinking: A review of the research [PDF]
Peer pressure is consistently implicated in the excessive drinking of college students. However, both theory and empirical findings suggest that peer pressure is a combination of three distinct influences: overt offers of alcohol, modeling, and social norms. Overt offers of alcohol can range from polite gestures to intense goading or commands to drink.
Kate B. Carey, Brian Borsari
openaire +3 more sources
In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi+5 more
wiley +1 more source
Guidelines for open peer review implementation
Open peer review (OPR) is moving into the mainstream, but it is often poorly understood and surveys of researcher attitudes show important barriers to implementation.
Tony Ross-Hellauer, Edit Görögh
semanticscholar +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia+17 more
wiley +1 more source
Online Brazilian Journal of Nursing 2007 Thanks to Peer Reviewers and Authors
The editor thanks the OBJN Reviewers and Authors for their competent service during the year 2007.
Isabel CF da Cruz
doaj +2 more sources