Results 81 to 90 of about 2,725,232 (305)
eLife, 2018 eLife is conducting a trial in which authors will decide how to respond to the issues raised during peer review.
Mark Patterson, Randy Schekman
doaj +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
FEBS Letters, EarlyView.Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
Cancer cell death induced by the NAD antimetabolite Vacor discloses the antitumor potential of SARM1
FEBS Letters, EarlyView.Vacor, a compound converted into the toxic metabolite Vacor adenine dinucleotide (VAD) by the nicotinamide salvage pathway enzymes NAMPT and NMNAT2, exhibits antitumor activity by inducing rapid and complete NAD depletion. We report that Vacor toxicity is limited to cell lines expressing high levels of SARM1, a NAD glycohydrolase.
Giuseppe Ranieri +5 more
wiley +1 more source
Peer review for the evaluation of the academic research: the Italian experience [PDF]
Peer review, that is the evaluation process based on judgments formulated by independent experts, is generally used for different goals: the allocation of research funding, the review of the research results submitted for publication in scientific ...
Anna Barbara +2 more
core
Enhancing Federal Agency Peer Review [PDF]
, 2016 Peer review, the process of reviewing a piece of scientific research for accuracy and reliability, is widely used in government. It serves an important function, allowing government agencies and other groups to assess the validity of research and ...
Peterson, Ian
core +1 more source
Life Otherwise at the Sea's Edge
Open Rivers, 2019 As part of a longer project on sea edges and coloniality, this essay studies ways of being that exceed the human, nonhuman, and colonial divide, and that find historical nodes of power and affective density at the boundaries of the Americas oceanic...
Macarena Gómez-Barris
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Efficacy of a meal sequence in patients with type 2 diabetes: a systematic review and meta-analysis
BMJ Open Diabetes Research & Care, 2022 Yuki Kataoka +3 more
doaj +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
The Convergence of Digital-Libraries and the Peer-Review Process
, 2005 Pre-print repositories have seen a significant increase in use over the past fifteen years across multiple research domains. Researchers are beginning to develop applications capable of using these repositories to assist the scientific community above ...
B. Gitanjali +16 more
core +2 more sources