Results 71 to 80 of about 1,292,600 (304)

Peer-to-Peer Multi-class Boosting [PDF]

open access: yes, 2012
We focus on the problem of data mining over large-scale fully distributed databases, where each node stores only one data record. We assume that a data record is never allowed to leave the node it is stored at. Possible motivations for this assumption include privacy or a lack of a centralized infrastructure. To tackle this problem, earlier we proposed
Hegedűs István   +4 more
openaire   +3 more sources

Peer relations linking overweight and obesity, and mediator factors among Turkish adolescents

open access: diamond, 2022
Başak Koca Özer   +8 more
openalex   +2 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

The Role of Technical Car Features in Managing and Promoting New Peer-to-Peer Car-Sharing Systems: Insights from Potential Users and Strategic Implications for Service Providers

open access: yesApplied Sciences
Peer-to-peer car-sharing systems are an evolving branch of urban mobility, aligning with global trends focused on sustainable development and reducing congestion in cities.
Katarzyna Turoń   +5 more
doaj   +1 more source

Sharing without laws: an exploration of social practices and ad hoc labeling standards in online movie piracy

open access: yesInternet Policy Review, 2016
This paper discusses self-labelling standards as sharing mediators in pirated versions of movies available online. Piracy has existed since the beginning of the film industry, challenging established rules and regulations.
Roberto Tietzmann, Liana Gross Furini
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Effectiveness of peer teaching in medical education: medical student’s perspective

open access: yesAdvances in Medical Education and Practice, 2018
Farhiya Omar, Maryam Zaheer, Muna AhmedFaculty of Medicine, St George’s Hospital Medical School, London, UKAs three clinical-year medical students in the United Kingdom, we were particularly intrigued by Elhassan’s1 research into a weekly ...
Omar F, Zaheer M, Ahmed M
doaj  

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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