Cytotoxic Indole Alkaloids against Human Leukemia Cell Lines from the Toxic Plant Peganum harmala
Toxins, 2015 Bioactivity-guided fractionation was used to determine the cytotoxic alkaloids from the toxic plant Peganum harmala. Two novel indole alkaloids, together with ten known ones, were isolated and identified.
Chunhua Wang +3 more
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Comparison of Peganum harmala L. leaves extract nanoformulations against herpes simplex virus type 1 guided by network pharmacology analysis [PDF]
Scientific ReportsHerpes simplex virus type 1 (HSV-1) is a highly prevalent viral infection with limited medications. Thus, search for safe and effective alternative treatments is urgently needed. Peganum harmala L. (P. harmala) praised with antiviral potential may afford
Basant A. Abou-Taleb +5 more
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Study of Methanol Extracts from Different Parts of Peganum harmala L. Using 1H-NMR Plant Metabolomics [PDF]
Journal of Analytical Methods in Chemistry, 2018 A nuclear magnetic resonance- (NMR-) based metabolomics method was used to identify differential metabolites of methanol extracts obtained from six parts of Peganum harmala L. (P. harmala), namely, the root, stem, leaf, flower, testa, and seed.
Yinping Li +5 more
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Alkaloids from cultivated plant of Peganum harmala L.
Mongolian Journal of Chemistry, 2014 Alkaloids such as 1H-cyclopenta(b) quinoline, 2.3.5.6.7.8-hexahydro-9-amino-; Vasicinone(1H-Pyrrоlo[2.1-b]quinazolin-9-one,3-hydroxy-2.3-dihydro) and harmine were isolated from cultivated plant of P. harmala.
S Javzan +4 more
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NMR-based metabolomic profiling of Peganum harmala L. reveals dynamic variations between different growth stages [PDF]
Royal Society Open Science, 2018 Xerophytes play an active role in preventing soil denudation and desertification in arid and semi-arid areas. Peganum harmala L. (Zygophyllaceae family), a seasonally growing, poisonous and drought-tolerant plant, is widely distributed in the Xinjiang ...
Yinping Li +5 more
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Pharmacological Studies of Syrian Rue (Peganum harmala L., Zygophyllaceae)
International Journal of Secondary Metabolite, 2018 Syrian rue (Peganum harmala L., Zygophyllaceae) has been used in traditional medicine of Central Asia, the Middle East, and Caucasus areas (Azerbaijan) for centuries, mainly as ritual and psychedelic plant.
Nazim A. Mamedov +2 more
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Peganum harmala Polysaccharide Mitigates LPS-Induced Inflammatory Response in Macrophages by Activating Autophagy Pathway. [PDF]
Food Sci NutrIn Xinjiang, Peganum harmala is a traditional medicinal plant and is widely cultivated as a Medicine‐Food plant. People add P. harmala to their teas and consume them for a higher immunity and a stronger body. Thus, in the present study, we explored the autophagic regulatory activity of LTP treatment and investigated its enhanced autophagy and exerted ...
Rejiepu M +6 more
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Molecules, 2016 Peganum harmala L., also known as Syrian rue or Pègano, is a herbaceous plant belonging to the Zygohpyllaceae family, and is widely used in traditional medicine. The chemical composition of essential oils of P.
Ida Apostolico +7 more
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Peganum harmala L.'s anti-growth effect on a breast cancer cell line. [PDF]
Biotechnol Rep (Amst), 2015 This research was done to evaluate the induction of apoptosis in MDA-MB-231 breast cancer cell line by Peganum harmala's extract, in which a significant amount of ß-carbolines is included. The apoptosis incidence was assessed through Annexin-V-Flous kit.
Hashemi Sheikh Shabani S +4 more
europepmc +5 more sources
Antimitotic and genotoxic effect on the meristematic cells of Allium cepa L. of the alkaloid and flavonoid fractions of the leaves of Peganum harmala L. from the Laghouat region, Algeria. [PDF]
International Journal of Minor Fruits, Medicinal and Aromatic Plants, 2021 Medicinal plants are an inexhaustible source of secondary metabolites, namely polyphenols including flavonoids, alkaloids and terpenoids, which generate various biological activities.
Yasmina Ouzid
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