Results 11 to 20 of about 10,402 (207)

Pegylated liposomal doxorubicin in ovarian cancer

open access: yesTherapeutics and Clinical Risk Management, 2009
Robert Strother1,2, Daniela Matei1–51Department of Medicine, 2Indiana University Melvin and Bren Simon Cancer Center, 3Department of Obstetrics and Gynecology, 4Department of Biochemistry and Molecular Biology, 5VA Roudebush Hospital Indiana ...
Robert Strother, Daniela Matei
doaj   +7 more sources

Meta-Analysis of Trials Comparing Gemcitabine and Pegylated Liposomal Doxorubicin for Treatment in Women with Progressive or Recurrent Ovarian Cancer

open access: yesCancer Biology & Medicine, 2009
OBJECTIVE To evaluate the efficacy and adverse effects of gemcitabine versus pegylated liposomal doxorubicin in patients with progressive or recurrent ovarian cancer.
Xia LIU, Li MA, Jinhui TIAN
doaj   +2 more sources

A randomized study of pegylated liposomal doxorubicin versus continuous-infusion doxorubicin in elderly patients with acute lymphoblastic leukemia: the GRAALL-SA1 study

open access: yesHaematologica, 2011
Background The prognosis of acute lymphoblastic leukemia in the elderly is poor. The GRAALL-SA1 phase II, randomized trial compared the efficacy and toxicity of pegylated liposomal doxorubicin versus continuous-infusion doxorubicin in patients 55 years ...
Mathilde Hunault-Berger   +19 more
doaj   +2 more sources

Pharmacokinetics, brain delivery, and efficacy in brain tumor-bearing mice of glutathione pegylated liposomal doxorubicin (2B3-101).

open access: yesPLoS ONE, 2014
Brain cancer is a devastating disease affecting many people worldwide. Effective treatment with chemotherapeutics is limited due to the presence of the blood-brain barrier (BBB) that tightly regulates the diffusion of endogenous molecules but also ...
Pieter J Gaillard   +10 more
doaj   +2 more sources

Exploring the Use of Pegylated Liposomal Doxorubicin (Caelyx®) as Pressurized Intraperitoneal Aerosol Chemotherapy [PDF]

open access: yesFrontiers in Pharmacology, 2019
Background: Peritoneal carcinomatosis is a common metastatic pattern in ovarian, gastric, colorectal, and appendiceal cancer; systemic chemotherapy is the current standard of care for peritoneal metastatic disease; however, in a subset of patients its ...
Manuela Robella   +7 more
doaj   +2 more sources

Pegylated and liposomal doxorubicin is associated with high mortality and causes limited cardiotoxicity in mice [PDF]

open access: yesBMC Research Notes, 2018
Objective We wanted to determine the impact of different doses of a pegylated and liposomal formulation of the cardiotoxic drug doxorubicin on cardiac function, fibrosis and survival in mice. The drug causes myocardial damage by producing reactive oxygen
Christoffer Stark   +3 more
doaj   +3 more sources

Prolonged use of pegylated liposomal doxorubicin in gynecologic malignancies

open access: yesGynecologic Oncology Reports, 2019
Pegylated liposomal doxorubicin (PLD) is a palliative treatment option for patients with recurrent gynecologic malignancies. It has an appealing toxicity profile and responses can be prolonged.
S. Yost, J.L. Konal, A.V. Hoekstra
doaj   +3 more sources

Safety and efficacy of pegylated liposomal doxorubicin in HIV-associated Kaposi’s sarcoma

open access: yesBiologics: Targets & Therapy, 2009
Francesca Cainelli1, Alfredo Vallone21Department of Internal Medicine, School of Medicine, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana; 2Infectious Diseases Unit, Annunziata Hospital, Cosenza, ItalyAbstract: Kaposi’s ...
Francesca Cainelli, Alfredo Vallone
doaj   +1 more source

Pegylated liposomal doxorubicin in patients with epithelial ovarian cancer [PDF]

open access: yesJournal of Ovarian Research, 2021
Objective To evaluate the efficacy and safety of PLD in treating of in patients who experience epithelial ovarian, fallopian tubal, and peritoneal cancer progression within 12 months after the first-line platinum-based therapy.
Zhen Yuan   +19 more
doaj   +3 more sources

Pegylated liposomal doxorubicin in the management of ovarian cancer

open access: yesTherapeutics and Clinical Risk Management, 2010
Gabriella Ferrandina1,2, Giacomo Corrado1, Angelo Licameli1, Domenica Lorusso2, Gilda Fuoco1, Salvatore Pisconti3, Giovanni Scambia2 1Gynecologic Oncology Unit, Department of Oncology, Catholic University of Campobasso, Campobasso, Italy; 2Gynecologic ...
Gabriella Ferrandina   +3 more
doaj   +6 more sources

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