Results 21 to 30 of about 10,402 (207)

New approaches in the management of advanced breast cancer – role of combination treatment with liposomal doxorubicin

Breast Cancer: Targets and Therapy, 2009
Iain RJ Macpherson, TR Jeffry EvansBeatson West of Scotland Cancer Centre, Glasgow, United KingdomAbstract: Metastatic breast cancer (MBC) remains a major cause of morbidity and mortality in women worldwide.
Iain RJ Macpherson, TR Jeffry Evans
doaj   +1 more source

Impact of PEGylated Liposomal Doxorubicin and Carboplatin Combination on Glioblastoma. [PDF]

Pharmaceutics, 2022
Glioblastoma is an incurable cancer with a 5-year survival chance of less than 5%. Chemotherapy is a therapeutic approach to treating the disease; however, due to the presence of the blood–brain barrier (BBB), the probability of success is low. To overcome this issue, nanoparticles are promising carriers for crossing the BBB and delivering drugs to the
Ghaferi M, Raza A, Koohi M, Zahra W, Akbarzadeh A, Ebrahimi Shahmabadi H, Alavi SE.   +6 more
europepmc   +6 more sources

Pegylated liposomal doxorubicin for relapsed epithelial ovarian cancer. [PDF]

Cochrane Database Syst Rev, 2023
Cancer of ovarian, fallopian tube and peritoneal origin, referred to collectively as ovarian cancer, is the eighth most common cancer in women and is often diagnosed at an advanced stage. Women with relapsed epithelial ovarian cancer (EOC) are less well and have a limited life expectancy, therefore maintaining quality of life with effective symptom ...
Newhouse R, Nelissen E, El-Shakankery KH, Rogozińska E, Bain E, Veiga S, Morrison J.   +6 more
europepmc   +4 more sources

Pegylated liposomal doxorubicin-induced palmar-plantar erythrodysesthesia

Gynecology and Minimally Invasive Therapy, 2018
Joana Moreira-Barros, Kuan-Gen Huang, Tsung-Hsun Tsai   +2 more
doaj   +3 more sources

Anaphylaxis to Pegylated Liposomal Doxorubicin: A Case Report [PDF]

West Indian Medical Journal, 2014
Liposomal doxorubicin is used for the treatment of various cancers like epithelial ovarian cancers, multiple myeloma and sarcomas. We report the first case of anaphylaxis to pegylated liposomal doxorubicin.
L R, Sharma, A, Subedi, B K, Shah
openaire   +2 more sources

Pegylated liposomal doxorubicin for myeloid neoplasms

Anti-Cancer Drugs, 2019
Pegylated liposomal doxorubicin (Peg-Dox) treatment resulted in a good outcome for patients with lymphoma and multiple myeloma, with reduced cardiotoxicity and an improved pharmacokinetic profile when compared to those of conventional doxorubicin. However, the use of Peg-Dox in myeloid neoplasms remains poorly studied.
Zhang, Cheng, Yao, Han, Kong, Pei-Yang, Liu, Yao, Gao, Lei, Gao, Li, Ma, Ying-Ying, Liu, Jun, Tan, Xu, Zhang, Xi   +9 more
openaire   +3 more sources

High dose and hepatobiliary dysfunction are associated with hand-foot syndrome in patients with lymphoma using pegylated liposomal doxorubicin: a retrospective study

BMC Pharmacology and Toxicology, 2021
Purpose In clinical practice, the risk factors for pegylated liposomal doxorubicin-related hand-foot syndrome remain unclear. The purpose of this study was to determine the risk factors associated with hand-foot syndrome in patients with lymphoma using ...
Yanfang Zhao, Wenjia Su, Guohua Liang, Xiaoyu Shan, Weiwei Ma, Dabei Tang, Liru Li, Xingjian Niu, Shu Zhao, Qingyuan Zhang, Wenhui Zhao   +10 more
doaj   +1 more source

Histological evidence for the cardiac safety of high-dose pegylated liposomal doxorubicin in a patient with HIV-associated Kaposi sarcoma: a case report and literature review

BMC Infectious Diseases, 2019
Background Pegylated liposomal doxorubicin plays an important role in the treatment of patients with severe refractory human immunodeficiency virus (HIV)-associated Kaposi sarcoma (KS).
Ayaka Ishihara, Shuji Hatakeyama, Jun Suzuki, Yusuke Amano, Teppei Sasahara, Masaki Toshima, Yuji Morisawa   +6 more
doaj   +1 more source

Tumor acidity-induced charge-reversal liposomal doxorubicin with enhanced cancer cell uptake and anticancer activity

Giant, 2021
Concerning that the polyethylene glycol surface layer of DOXIL hinders cancer cell uptake, thus leading to low anticancer activity, it is of great importance to promote the cancer cell uptake of liposomal doxorubicin.
Jinpeng Yang, Zihe Yin, Yincheng Chang, Hua Wang, Jiang-Fei Xu, Xi Zhang   +5 more
doaj   +1 more source

A tale of the two PEGylated liposomal doxorubicins

OncoTargets and Therapy, 2015
Hunghsueh Chou,1,4 Hao Lin,2,4 Jacqueline M Liu31Department of Obstetrics and Gynecology, Linkou Chang Gung Memorial Hospital, Linkou, Taiwan; 2Department of Obstetrics and Gynecology, Kaohsiung Chang Gung Memorial Hospital, Linkou, Taiwan; 3TTY Oncology Translational Research Center, TTY Biopharm, Taipei, Taiwan; 4Chang Gung University College of ...
Chou,Hunghsueh, Lin,Hao, Liu,Jacqueline M   +2 more
openaire   +4 more sources