Results 61 to 70 of about 986,642 (356)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Characteristics of NH₃–H₂ Reducing Pellets

Metals
The reduction of hematite with ammonia is a potentially environmentally friendly method of ironmaking. Previous studies on ammonia reduction of pellets typically involved samples weighing only 2.8 g and lacked detailed activation energy analysis for the ...
Xiaoping Zhang, Zihao Fan, Ao Mi, Junqiang Cong, Zhenghong Hu, Jialong Yang, Baoliang Wen   +6 more
doaj   +1 more source

Torrefaction and Densification of Wood Sawdust for Bioenergy Applications

Fuels, 2022
In this study, wood sawdust as waste residue from wood processing mills was pretreated using torrefaction to improve fuel properties and densified to facilitate transportation.
Peyman Alizadeh, Lope G. Tabil, Phani K. Adapa, Duncan Cree, Edmund Mupondwa, Bagher Emadi   +5 more
doaj   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Docosahexaenoic Acid Included in Layer Feed as an Unextracted Aurantiochytrium limacinum Biomass Is Efficiently Transferred to Eggs When Provided in Mash or Pellet Form

Journal of Applied Poultry Research, 2019
SUMMARY: Pelleting is commonly used in the production of poultry feed as it can reduce waste, kill pathogenic bacteria, and improve productivity. However, high temperatures used during production can negatively impact some feed ingredients.
J.D. Keegan, D. Currie, A. Knox, C.A. Moran   +3 more
doaj   +1 more source

Monitoring soil moisture from middle to high elevation in Switzerland: set-up and first results from the SOMOMOUNT network [PDF]

Hydrology and Earth System Sciences, 2017
Besides its important role in the energy and water balance at the soil–atmosphere interface, soil moisture can be a particular important factor in mountain environments since it influences the amount of freezing and thawing in the subsurface and can ...
C. Pellet, C. Hauck
doaj   +1 more source

Pellet fuelling with edge-localised modes controlled by external magnetic perturbations in MAST

, 2014
The fuelling of plasmas by shallow frozen pellets with simultaneous mitigation of edge localised modes (ELM) by external magnetic perturbation is demonstrated on the MAST tokamak. Post-pellet particle loss is dominated by ELMs and inter-ELM gas fuelling.
Dunai, D, Field, A R, Garzotti, L, Gurl, C, Kirk, A, Lupelli, I, Naylor, G, Thornton, A, Valovic, M   +8 more
core   +1 more source

Visual histological grading system for the evaluation of in vitro-generated neocartilage [PDF]

, 2006
Here we present the development of a visual evaluation system for routine assessment of in vitro-engineered cartilaginous tissue. Neocartilage was produced by culturing human articular chondrocytes in pellet culture systems or in a scaffold-free ...
Barbero, Andrea, Fitzsimmons, James S., Grogan, Shawn Patrick, Mainil-Varlet, Pierre, Martin, Ivan, O`Driscoll, Shawn, Rieser, Franz, Winkelmann, Verena   +7 more
core   +1 more source