Results 61 to 70 of about 505,481 (268)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
PELLETS AND PELLETIZATION TECHNIQUES: A CRITICAL REVIEW
International Research Journal of Pharmacy, 2016 In the pharmaceutical industry , pellets can be defined a s small, free - flowing, spherical particulates manufactured by the agglomeration of fine powders or granules of drug substances and excipients using appropriate processing equipment. Pelletization has gained a great interest in recent years due to its vario us advantages over other similar ...
Ratul Deb, Abdul Baquee Ahmed
openaire +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Combustion Analysis of Mixed Secondary Fuel Produced from Agro-Biomass and RDF in a Fluidized Bed
EnergiesIn recent decades, there has been growing interest in the thermal conversion of various alternative fuels, such as biomass and waste-derived fuels. One of the technological solutions for the so-called direct co-combustion of fuels is to create mixtures ...
Konrad Kaczyński, Piotr Pełka
doaj +1 more source
Evaluation of Mechanical Parameters of Pellets
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2016 The paper dealt with the evaluation of mechanical properties of the cylinder wheat straw, rapeseed straw and 50/50 % mixed wheat and rapeseed straw pellet samples. The pellets were made by the granulating machine MGL 200 (Kovonovak).
Ľubomír Kubík +2 more
doaj +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Production of Low Emission Pellet from Coco Peat Waste
CORD, 2013 Study was conducted on coco peat as a low emission pellet form biomass fuel alternative to produce synthetic gas (syngas) through gasification process in use for other processes.
Rizal Alamsyah
doaj +1 more source
Bioethanol Production from Sugarcane Bagasse Using Neurospora intermedia in an Airlift Bioreactor
International Journal of Renewable Energy Development, 2020 Bagasse as solid waste in sugarcane industry can be utilized as one of the potential raw materials in the bioprocess industry. This research aims to investigate the conversion of bagasse to bioethanol using simultaneous saccharification and fermentation ...
Elvi Restiawaty +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source