Results 61 to 70 of about 560,758 (346)

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Risperidone Pellets, Pycnogenol®, and Glucomannan Gummy Formulation for Managing Weight Gain and ADHD in Autistic Children

open access: yesPharmaceutics
Gummy formulations are defined as gradually or slowly released solid oral dosage forms. Risperidone is an atypical antipsychotic medication used to treat schizophrenia and autism-related irritability.
Rawand M. Daghmash   +2 more
doaj   +1 more source

DEVELOPMENT OF WOOD-BASED PRODUCTS WORLDWIDE [PDF]

open access: yesPro Ligno, 2015
The tendency in recent decades for manufacturing plants of semi-finished products such as composite panels, has been to invest in order to achieve high production capacities (>2,000 m³/day for panels and >3,000 t/day for paper with one line). The trend
Marius C. BARBU, Michael PAULITSCH
doaj  

Consumer attitudes towards the use of pellets in function of energetic efficiency [PDF]

open access: yesMarketing (Beograd. 1991), 2020
Modern living conditions are characterized with concern for environmental protection and sustainable development, which implies an increase in environmental awareness of consumers and a continuous change in consumer attitudes with a goal to adopt ...
Nikolić-Ristić Dragana, Đokić Nenad
doaj  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Ultrasound-assisted extraction of itraconazole from pellets: an efficient approach for the recovery of active pharmaceutical compounds from solid dosage forms

open access: yesFrontiers in Analytical Science
IntroductionItraconazole is a widely used broad-spectrum antifungal drug on a global scale. However, its poor water solubility necessitates the development of advanced formulations for its effective use.
Patricia G. Ferreira   +5 more
doaj   +1 more source

Comparação entre formas físicas da ração no desempenho de leitões do desmame aos setenta dias de idade Comparison between different shapes of ration in the performance of weaning pigs up to seventy days

open access: yesCiência Rural, 1995
Um estudo foi realizado no Departamento de Zootecnia da Universidade Federal de Santa Maria, com o objetivo de avaliar o efeito de três formas físicas de ração sobre o desempenho de leitões, do desmame (28 dias de idade) até 70 dias de idade.
Gerson Guarez Garcia   +1 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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