Results 41 to 50 of about 5,652 (210)

Epidemiology of Pemphigus

open access: yesJID Innovations, 2021
Pemphigus is an epidemiologically heterogeneous group of autoimmune bullous diseases comprising pemphigus vulgaris (PV), pemphigus foliaceus, paraneoplastic pemphigus, IgA pemphigus, and pemphigus herpetiformis.
Khalaf Kridin, Enno Schmidt
doaj   +1 more source

Lots of autoantibodies equal lupus? [PDF]

open access: yes, 2013
Autoantibodies may be found years before an autoimmune disease becomes clinically apparent. For systemic lupus erythematosus (SLE), those to RNA-binding proteins, to phospholipids, and to double-stranded DNA, in particular, have been found in sera of SLE
Aringer, M, Vital, E
core   +1 more source

Data on HLA class I/II profile in Brazilian pemphigus patients

open access: yesData in Brief, 2016
Pemphigus are blistering autoimmune diseases related with genetic and environmental factors. Here we describe HLA genotyping in pemphigus patients. First, we review the HLA class I/II data on pemphigus reported in Brazilian samples and then present the ...
Maria José Franco Brochado   +4 more
doaj   +1 more source

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

open access: yes, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R.   +9 more
core   +1 more source

Loss of flotillin expression results in weakened desmosomal adhesion and Pemphigus vulgaris-like localisation of desmoglein-3 in human keratinocytes [PDF]

open access: yes, 2016
Desmosomes are adhesion plaques that mediate cell-cell adhesion in many tissues, including the epidermis, and generate mechanical resistance to tissues. The extracellular domains of desmosomal cadherin proteins, desmogleins and desmocollins, are required
Ali, Jawahir   +7 more
core   +1 more source

Autoimmuunsed villilised haigused [PDF]

open access: yes, 2006
Villiliste haiguste rühma patogeneetiliseks aluseks on autoantikehade tekkimine epi der mise või dermoepidermaalse ühendusjoone normaalsete komponentide vastu. Kuigi hai gu sed erinevad omavahel haigete keskmise vanuse, kliinilise pildi ja histoloogilise
Kaur, Sirje, Pärna, Ene
core   +2 more sources

Case for diagnosis [PDF]

open access: yes, 2012
We report a clinical case of a rare variant of pemphigus - pemphigus herpetiformis - which combines the clinical features of dermatitis herpetiformis with the immunological findings of pemphigus.
Alves, R.   +3 more
core   +1 more source

Adjuvant therapy of severe and/or refractory bullous pemphigoid with immunoadsorption – A prospective monocenter pilot study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives Bullous pemphigoid (BP) is the most common autoimmune blistering disease in the Western world. While remission is achieved in the majority of BP patients by long‐term use of corticosteroids with or without immunomodulants/immunosuppressants, national and international guidelines recommend adjuvant immunoadsorption (IA)
Maike M. Holtsche   +7 more
wiley   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

open access: yesJournal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini   +9 more
wiley   +1 more source

Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris [PDF]

open access: yes, 2012
Pemphigus vulgaris (PV) is an autoimmune blistering skin disease characterized by suprabasal acantholysis and by autoantibodies against desmoglein 3 localized on desmosomes. In addition, caspases also seem to participate in this blistering disease. Focal
España, A. (Agustín)   +3 more
core   +1 more source

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