Results 171 to 180 of about 5,901 (191)
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Journal of Hepatology, 2006
The administration of a methionine and choline deficient (MCD) diet to mice serves as an animal model of NASH. The multidrug resistant 2 (Mdr2) P-glycoprotein encodes for the canalicular phospholipid transporter, and Mdr2 (+/-) mice secrete 40% less phosphatidylcholine than wild-type mice.
Alexander C, Igolnikov, Richard M, Green
exaly +3 more sources
The administration of a methionine and choline deficient (MCD) diet to mice serves as an animal model of NASH. The multidrug resistant 2 (Mdr2) P-glycoprotein encodes for the canalicular phospholipid transporter, and Mdr2 (+/-) mice secrete 40% less phosphatidylcholine than wild-type mice.
Alexander C, Igolnikov, Richard M, Green
exaly +3 more sources
The Journal of Nutritional Biochemistry, 2015
Demand for the vital nutrient choline is high during lactation; however, few studies have examined choline metabolism and requirements in this reproductive state. The present study sought to discern the effects of lactation and varied choline intake on maternal biomarkers of choline metabolism and breast milk choline content.
Crystal, Davenport +10 more
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Demand for the vital nutrient choline is high during lactation; however, few studies have examined choline metabolism and requirements in this reproductive state. The present study sought to discern the effects of lactation and varied choline intake on maternal biomarkers of choline metabolism and breast milk choline content.
Crystal, Davenport +10 more
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Nutrition Research, 2018
Maternal metabolism during gestation may depend on nutrient intake but also on polymorphism of genes encoding enzymes involved in metabolism of different nutrients. Data on choline or carnitine metabolism in pregnant women are scarce. We hypothesized that (1) choline intake in Polish pregnant women is inadequate and (2) choline and carnitine metabolism
Agata Chmurzynska +9 more
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Maternal metabolism during gestation may depend on nutrient intake but also on polymorphism of genes encoding enzymes involved in metabolism of different nutrients. Data on choline or carnitine metabolism in pregnant women are scarce. We hypothesized that (1) choline intake in Polish pregnant women is inadequate and (2) choline and carnitine metabolism
Agata Chmurzynska +9 more
openaire +2 more sources
Psychiatry Research, 2009
The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in
Heyao, Li +7 more
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The present study included a total of 628 patients with schizophrenia and 588 healthy controls to replicate the genetic association between the PEMT gene and schizophreia. However, our results in this study failed to confirm our earlier finding that the C allele was preferentially transmitted by parents to their offspring affected with schizophrenia in
Heyao, Li +7 more
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Role of Hepatic PEMT and Dietary Choline in the Development of Atherosclerosis
2017Phosphatidylethanolamine N-methyltransferase (PEMT) is a hepatic enzyme that converts phosphatidylethanolamine to phosphatidylcholine. Pemt-/- mice are protected from obesity and insulin resistance, a phenotype that is reversed with dietary choline supplementation.
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Biochimica et biophysica acta, 2001
Phosphatidylethanolamine N-methyltransferase (PEMT) catalyzes the conversion of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) in a series of three methylation reactions. Preliminary studies of PEMT in humans led to the cloning of three cDNAs each of which has a different 5' untranslated region (5'UTR). To determine the origin of PEMT splice
D J, Shields, L B, Agellon, D E, Vance
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Phosphatidylethanolamine N-methyltransferase (PEMT) catalyzes the conversion of phosphatidylethanolamine (PE) to phosphatidylcholine (PC) in a series of three methylation reactions. Preliminary studies of PEMT in humans led to the cloning of three cDNAs each of which has a different 5' untranslated region (5'UTR). To determine the origin of PEMT splice
D J, Shields, L B, Agellon, D E, Vance
openaire +1 more source
285 – A study of the PEMT gene in schizophrenia
Schizophrenia Research, 2008H.-Y. Zhang +6 more
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2022 IEEE International Conference on Communications, Control, and Computing Technologies for Smart Grids (SmartGridComm), 2022
Yuanliang Li +6 more
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Yuanliang Li +6 more
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EMT, MET, Plasticity, and Tumor Metastasis
Trends in Cell Biology, 2020Anna M Chiarella +2 more
exaly