FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
POINTER:a GDPR-compliant framework for human pentesting (for SMEs) [PDF]
, 2018 Penetration tests have become a valuable tool in any organisation’s arsenal, in terms of detecting vulnerabilities in their technical defences. Many organisations now also “penetration test” their employees, assessing their resilience and ability to ...
Archibald, Jacqueline, Renaud, K.
core
Estimating Hydraulic Conductivity of Overconsolidated Soils Based on Piezocone Penetration Test (PCPT) [PDF]
, 2021 Binyam Bekele +3 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Developing a Regionally Adaptable CPT-SPT Correlation Using Linear Regression and Genetic Algorithms
Applied SciencesEstablishing a correlation between the Cone Penetration Test (CPT) and the Standard Penetration Test (SPT) is of significant importance for geotechnical engineering practice. A novel correlation between CPT-qt and SPT-N60 based on a genetic algorithm (GA)
Shuai Fang +3 more
doaj +1 more source
Cone penetration test in a virtual calibration chamber
, 2014 Cone penetration test (CPT) is a fast and reliable site investigation tool for exploring soils and soft ground. While the interpretation of the test results in clay has advanced considerably from a theoretical and numerical viewpoint that of tests in ...
J. Butlanska
semanticscholar +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Damage to metallic samples produced by measured lightning currents [PDF]
, 1991 A total of 10 sample disks of 2024-T3 aluminum and 4130 ferrous steel were exposed to rocket-triggered lightning currents at the Kennedy Space Center test site.
Fisher, Richard J., Schnetzer, George H.
core +1 more source
Machine Learning Techniques for Soil Characterization Using Cone Penetration Test Data [PDF]
, 2023 Ayele Tesema Chala, Richard Ray
openalex +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source