Results 171 to 180 of about 460,006 (298)

An Injectable Electroactive Hydrogel Engineered for Stable Bioelectronic Interfaces

Advanced Materials Interfaces, EarlyView.
Injectable electroconductive hydrogels enable soft, conformal, and stable bioelectronic interfaces for electroceutical therapies. A catechol‐modified hyaluronic acid/alginate/edge‐functionalized graphene platform combines wet adhesion, shear‐thinning injectability, tissue‐matched mechanics, and electrochemical functionality.
Ying Zhou, Peng Zheng, Beverley Cheung, Chien Yu Huang, Greg Ryder, Jonathan R Clark, D S Abdullah Al Maruf, Yi‐Hui Wu, Ming‐Dou Ker, Xufeng Huang, Gordon G Wallace, Xiao Liu   +11 more
wiley   +1 more source

A penicillin-binding protein inhibitor series to target drug-resistant Neisseria gonorrhoeae. [PDF]

Nat Microbiol
Uehara T, Zulli AL, Miller B, Avery LM, Boyd SA, Chatwin CL, Chu GH, Drager AS, Edwards M, Emeigh Hart SG, Line NJ, Myers CL, Rongala G, Stevenson A, Uehara K, Yi F, Wang B, Liu Z, Wang M, Zhao Z, Zhou X, Zhao H, Stratton CM, Bala S, Davies C, Tkavc R, Jerse AE, Pevear DC, Burns CJ, Daigle DM, Condon SM.   +30 more
europepmc   +1 more source

Development of Nanoflare Nanosensors for Monitoring Cellular Insulin mRNA in Beta Cells and Islets

Advanced Materials Technologies, EarlyView.
This study presents the design and application of In2‐NF probes for detecting insulin mRNA in beta cells and islets. Using spherical nucleic acid‐coated gold nanoparticles, the probes offer strong fluorescent signals upon hybridization. Their performance is validated across 2D and 3D cultures and rat islets, demonstrating sensitive, real‐time mRNA ...
Yana Hu, Qizheng Zhang, Tianli Hu, Juewen Liu, Hongxing Fu, Xin Zhao, Zijiang Yang, Chenjie Xu   +7 more
wiley   +1 more source

Emergence of Klebsiella pneumoniae Carbapenemase-Producing K. pneumoniae with Penicillin-Binding Protein 3 Insertions, Taiwan, 2021. [PDF]

Emerg Infect Dis
Long T, Lovey A, Sanborn L, Zhao Y, Bulman ZP, Lin YT, Chen L.   +6 more
europepmc   +1 more source

An Accessible Microfluidic Platform for the Generation of Polarized Brain Organoids

Advanced Materials Technologies, EarlyView.
This study presents an accessible double‐gradient microfluidic device that enables controlled morphogen delivery and spatially polarized differentiation in brain organoids. By integrating a pump‐free design and stable fabrication method, the platform generates dorsal–ventral neuronal asymmetry, offering a reproducible and versatile approach to model ...
Daniel Pérez‐Calixto, Manuel Alejandro Vazquez Valle, Mitzi Pérez‐Calixto, Cindy Peto‐Gutiérrez, Iván Velasco, Genaro Vázquez‐Victorio, Itzel Escobedo‐Avila   +6 more
wiley   +1 more source

Respiratory syncytial virus increases the virulence of Streptococcus pneumoniae by binding to penicillin binding protein 1a. A new paradigm in respiratory infection.

American Journal of Respiratory and Critical Care Medicine, 2014
C. Smith, Sara M. Sandrini, S. Datta, P. Freestone, Sulman Shafeeq, P. Radhakrishnan, Gwyneth Williams, Sarah M. Glenn, O. Kuipers, R. Hirst, A. Easton, P. Andrew, C. O’Callaghan   +12 more
semanticscholar   +1 more source

Penicillin-Binding Protein-4 (PBP4) of <i>Staphylococcus aureus</i> and Its Role in β-Lactam Resistance: An Update. [PDF]

Microorganisms
Satishkumar N, Chatterjee SS.
europepmc   +1 more source

Topography‐Regulated Screening Platform for Myoblast Contact Guidance

Advanced Materials Technologies, EarlyView.
This study develops a topography‐regulated screening platform (12 gradients in 96‐topography‐well plate) enabling analysis of skeletal muscle morphogenesis. The topography‐induced cell morphology changed, cell polarization, and myotube differentiation, establishing an evaluative framework for generating pathologically relevant myotube phenotypes to ...
Tianqi Feng, Torben A.B. van der Boon, Savannah Amy Haupt, Adam Jones, Yanjing Ji, Theo G. Van Kooten, Patrick van Rijn   +6 more
wiley   +1 more source

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function

Proceedings of the National Academy of Sciences of the United States of America, 2013
L. H. Otero, A. Rojas-Altuve, L. I. Llarrull, C. Carrasco-López, Malika Kumarasiri, E. Lastochkin, Jennifer Fishovitz, Matthew Dawley, D. Hesek, Mijoon Lee, J. Johnson, J. Fisher, Mayland Chang, S. Mobashery, J. Hermoso   +14 more
semanticscholar   +1 more source

Integrated framework for targeting dynamic penicillin-binding protein 2a via ensemble structural biology and deep generative modeling. [PDF]

Front Microbiol
Pang T, Zhang X, Zhou Y, Yang J.
europepmc   +1 more source