Results 111 to 120 of about 1,197,885 (388)
The impact of penicillin skin testing on clinical practice and antimicrobial stewardship.
Journal of Hospital Medicine, 2013 BACKGROUND Penicillin skin testing (PST) is a simple and reliable way of diagnosing penicillin allergy. After being off the market for 4 years, penicilloyl-polylysine was reintroduced in 2009 as PRE-PEN. We describe the negative predictive value (NPV) of
R. Rimawi +7 more
semanticscholar +1 more source
Diversity among clinical isolates of penicillin-resistant Streptococcus mitis: indication for a PBP1-dependent way to reach high levels of penicillin resistance [PDF]
, 2010 A total of 12 non-epidemiologically related clinical isolates of Streptococcus mitis that showed different levels of resistance to penicillin were studied.
Emilia Cercenado +7 more
core +2 more sources
Molecular Oncology, EarlyView.Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop +10 more
wiley +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 1975 The varied effects of beta-lactam antibiotics on cell division, cell elongation, and cell shape in E. coli are shown to be due to the presence of three essential penicillin binding proteins with distinct roles in these three processes.
B. Spratt
semanticscholar +1 more source
Facilitation of penicillin haptenation to serum proteins. [PDF]
, 1993 Traditionally, penicillin binding to serum proteins was believed to be a passive chemical process; however, it appears to be facilitated by serum factors.
Adkinson, N. Franklin, Jr. +2 more
core +3 more sources
Molecular Oncology, EarlyView.Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed +8 more
wiley +1 more source
Penicillin to prevent recurrent leg cellulitis.
New England Journal of Medicine, 2013 BACKGROUND Cellulitis of the leg is a common bacterial infection of the skin and underlying tissue. We compared prophylactic low-dose penicillin with placebo for the prevention of recurrent cellulitis.
K. Thomas +13 more
semanticscholar +1 more source
Antibiotic Susceptibility of Black-Pigmented \u3cem\u3eBacteroides\u3c/em\u3e Isolates from the Human Oral Cavity [PDF]
, 1982 The minimal inhibitory concentrations of penicillin and six other antibiotics were determined for 66 oral black-pigmented Bacteroides isolates by using the National Committee for Clinical Laboratory Standards proposed standard agar dilution technique ...
Hohenfeldt, Paul R. +2 more
core +1 more source
Developments in diagnostics and antibiotic resistance of coagulase positive, maltose negative staphylococci from milk of dairy cows [PDF]
, 2019 In South Africa, as is done with routine Veterinary diagnostics worldwide, focus is on a fast turnaround time and relatively low cost. Staphylococci are identified using the coagulase test (Staphylase test, Oxoid). In more recent years, further diagnosis
Donkin, Edward F. +4 more
core +1 more source
Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma
Molecular Oncology, EarlyView.GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski +19 more
wiley +1 more source