Results 111 to 120 of about 835,846 (358)
Fleming’s penicillin producing strain is not Penicillium chrysogenum but P. rubens
Penicillium chrysogenum is a commonly occurring mould in indoor environments and foods, and has gained much attention for its use in the production of the antibiotic penicillin.
J. Houbraken, J. Frisvad, R. Samson
semanticscholar +1 more source
HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang+11 more
wiley +1 more source
THE METABOLISM OF THE PENICILLIA IN RELATION TO PENICILLIN BIOSYNTHESIS [PDF]
H. R. V. Arnstein, P. T. Grant
openalex +1 more source
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He+5 more
wiley +1 more source
Severe streptococcal infections are commonly treated with intravenous followed by oral penicillin (pheneticillin) therapy. However, switching from iv to oral therapy is complicated by the variability in oral pheneticillin absorption.
Anneke C. Dijkmans+5 more
doaj +1 more source
The Estimation of Penicillins and Penicillin Destruction [PDF]
J. M. T. Hamilton-Miller+2 more
openaire +3 more sources
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy+14 more
wiley +1 more source
Anemia falciforme e infecções Sickle cell disease and infection
OBJETIVO: A alta prevalência de anemia falciforme em nosso meio e a elevada morbimortalidade por infecções associada a esta condição estimularam a realização deste artigo de revisão.
Dayana V. P. Di Nuzzo+1 more
doaj +1 more source