Results 131 to 140 of about 1,198,632 (386)

The Frequency of MRSA carriers in health care workers in Gorgan, North of Iran [PDF]

open access: yes, 2011
Methicillin resistant Staphylococcus aureus (MRSA) is one of the most important pathogen in hospitals. Healthcare personnel are the main source of nosocomial infections and identification and control of MRSA carriers can reduce incidence of infections ...
Alang, S.R.   +4 more
core  

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

Limited Exposure to Social Isolation does not Affect the Spike Frequency and Amplitude of Penicillin-induced Epileptiform Activity in Adolescent Rats

open access: yesArchives of Epilepsy
Objective: It is known that the stress experienced during this period increases the risk of seizures. This study, it was investigated the effect of limited social isolation (SI) stress experienced in early life on penicillin-induced epileptiform activity.
Seval Müsüroğlu Keloğlan   +5 more
doaj   +1 more source

Microwave-assisted synthesis and development of novel penicillinoate@copper metal-organic frameworks as a potent antibacterial agent

open access: yesFrontiers in Chemistry
Recently, nanoscience, especially metal–organic frameworks (MOFs), has been used to increase the effectiveness and properties of drugs. In this study, by using microwave irradiation; penicillin, which is a known antibiotic; and copper metal–organic ...
Adnan Hashim Abdulkadhim   +12 more
doaj   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Bibliometric analysis of the trends and evolution in β-lactam allergy research

open access: yesJournal of Allergy and Clinical Immunology: Global
Background: β-Lactams remain the most reported drug allergy globally, with the volume and diversity of related drug allergy research continuing to accumulate.
Hugo W.F. Mak, MBBS   +3 more
doaj   +1 more source

What are the essential components of HIV treatment and care services in low and middle-income countries: an overview by settings and levels of the health system?

open access: yes, 2012
OBJECTIVES: To review and summarize the essential components of HIV treatment and care services in low and middle-income countries (LMICs). METHODS: Literature review and reflection on programmatic experience.
Droti, Benson   +3 more
core   +1 more source

Targeting of PTP4A3 overexpression sensitises HGSOC cells towards chemotherapeutic drugs

open access: yesMolecular Oncology, EarlyView.
In HGSOC with normal KRAS expression, high PTP4A3 expression regulates autophagy activation. Conversely, in HGSOC with high KRAS expression, KRAS dictates autophagy control, and PTP4A3 is not required. When high PTP4A3 expression is inhibited, HGSOC cells are preferentially sensitised towards DNA‐damaging agents.
Ana López‐Garza   +3 more
wiley   +1 more source

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