Results 201 to 210 of about 561,009 (296)

Activity-based protein profiling of serine hydrolases and penicillin-binding proteins in Enterococcus faecium. [PDF]

FEMS Microbes
Grunnvåg JS, Hegstad K, Lentz CS.
europepmc   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, EarlyView.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

<i>k</i>_inact/<i>K</i>_I Value Determination for Penicillin-Binding Proteins in Live Cells. [PDF]

ACS Infect Dis
Shirley JD, Gillingham JR, Nauta KM, Diwakar S, Carlson EE.   +4 more
europepmc   +1 more source

Multiple Low-Reactivity Class B Penicillin-Binding Proteins Are Required for Cephalosporin Resistance in Enterococci. [PDF]

Antimicrob Agents Chemother, 2020
Djorić D, Little JL, Kristich CJ.
europepmc   +1 more source

Dynamic Modulation of the Microenvironment Promotes Functional Maturation of Engineered Tissues

Advanced Healthcare Materials, EarlyView.
Engineered tissues lack the dynamic microenvironment of native tissues. A biocompatible, diffusible small molecule to dynamically modulate tissue microenvironments during maturation is used. Timing‐dependent modulation yields distinct outcomes, producing thicker, more native‐like blood vessels, stronger and more mature cardiac tissues, and optimized ...
Eric Silberman, Hadas Oved, Itay Gil, Amgad Marzook, Ester Sapir Baruch, Yahel Shechter, Assaf Shapira, Tal Dvir   +7 more
wiley   +1 more source

Unveiling the Relationship between Ceftobiprole and High-Molecular-Mass (HMM) Penicillin-Binding Proteins (PBPs) in Enterococcus faecalis. [PDF]

Antibiotics (Basel)
Conti P, Lazzaro LM, Longo F, Lenzo F, Giardina A, Fortuna SA, Stefani S, Campanile F.   +7 more
europepmc   +1 more source

Enterobactin- and salmochelin-β-lactam conjugates induce cell morphologies consistent with inhibition of penicillin-binding proteins in uropathogenic Escherichia coli CFT073. [PDF]

Chem Sci, 2021
Sargun A, Johnstone TC, Zhi H, Raffatellu M, Nolan EM.   +4 more
europepmc   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Clinical isolates of <i>Streptococcus mitis/oralis</i>-related species with reduced carbapenem susceptibility, harboring amino acid substitutions in penicillin-binding proteins in Japan. [PDF]

Antimicrob Agents Chemother
Sarangi J, Ido A, Ito M, Iinuma C, Doyama Y, Jin W, Wachino J-i, Suzuki M, Iguchi M, Yagi T, Arakawa Y, Kimura K.   +11 more
europepmc   +1 more source

A Small Molecule Inhibitor of CTP Synthetase Identified by Differential Activity on a Bacillus subtilis Mutant Deficient in Class A Penicillin-Binding Proteins. [PDF]

Front Microbiol, 2020
Emami K, Wu LJ, Errington J.
europepmc   +1 more source