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Penicillin-binding proteins inStreptococcus mitis

Current Microbiology, 1992
The penicillin-binding protein (PBP) profiles of penicillin-susceptible and-resistant clinical isolates ofStreptococcus mitis varied even with strains with similar minimal inhibitory concentrations (MICs).S. mitis NCTC 10712 was used as a DNA recipient to investigate PBP alterations which could occur as a result of spontaneous mutation and intra- and ...
Elsa Potgieter   +2 more
openaire   +1 more source

Purification of Streptococcus faecium penicillin binding protein 5, a multifunctional penicillin-binding protein.

Microbiologica, 1986
Penicillin-binding protein 5 of Streptococcus faecium has been solubilized and partially separated from other membrane proteins by covalent affinity chromatography. PBP 5 was successively purified to homogeneity by resolution on SDS-polyacrylamide gel, elution and renaturation of penicillin-binding activity.
A. Grossato   +4 more
openaire   +2 more sources

Penicillin-Binding Proteins of Gram-Negative Bacteria

Clinical Infectious Diseases, 1988
beta-Lactam antibiotics exert their antibacterial effects by inactivating the high-molecular-weight penicillin-binding proteins (PBPs) that are responsible for the final stages of peptidoglycan biosynthesis. The availability of the amino acid sequences of several low-molecular-weight PBPs, high-molecular-weight PBPs, and active-site serine beta ...
B G, Spratt, K D, Cromie
openaire   +2 more sources

A Method to Assay Penicillin-Binding Proteins

2008
Key enzymes that assemble the bacterial cell wall are also the target of the Beta-lactam class of antibiotics. The covalent binding of labeled penicillin to these proteins has been used in numerous studies in drug discovery, antibiotic mechanisms of action and resistance, and cell wall physiology.
Michael J, Pucci, Thomas J, Dougherty
openaire   +2 more sources

Penicillin-Binding Protein 5 of Escherichia coli

2013
Refereed/Peer ...
Malika Kumarasiri   +2 more
openaire   +2 more sources

Pathogenesis, epidemiology and control of Group A Streptococcus infection

Nature Reviews Microbiology, 2023
Stephan Brouwer, Bodie Curren
exaly  

Penicillin-binding Proteins

RCSB Protein Data Bank, 2002
openaire   +1 more source

Penicillin Binding Protein

RCSB Protein Data Bank
Gauri Patel, Helen Gao
openaire   +1 more source

Penicillin-binding proteins of Bacteroides fragilis

Journal of Antimicrobial Chemotherapy, 1984
BOTTA GA   +2 more
openaire   +3 more sources

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