Results 101 to 110 of about 205,895 (382)

Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]

, 2002
Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Casey, Lorraine A., Galt, Ronald H. B., Hadfield, Peter S., Page, Michael I., Vilanova, Bartholomew   +4 more
core   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

First case of the succesful treatment of actinomicosis of the knee in a child

Журнал инфектологии, 2019
Objectives. Actinomycosis in children has not been studied enough, the number of publications is limited. Actinomycosis of the knee joint is very rare, the disease mimics tuberculosis or malignant neoplasms, which can lead to late diagnosis and ...
O. P. Kozlova, N. V. Isaeva, Yu. L. Avdeenko, N. N. Klimko   +3 more
doaj   +1 more source

Superbugs and Superdrugs: A history of MRSA [PDF]

, 2008
Annotated and edited transcript of a Witness Seminar held on 11 July 2006. Introduction by Professor David Greenwood, University of Nottingham.First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2008.©The Trustee of the ...
Reynolds, LA, Tansey, EM
core  

Prevalence and predictors of postdischarge antibiotic use following mastectomy [PDF]

, 2017
OBJECTIVESurvey results suggest that prolonged administration of prophylactic antibiotics is common after mastectomy with reconstruction. We determined utilization, predictors, and outcomes of postdischarge prophylactic antibiotics after mastectomy with ...
Fraser, Victoria J, Nickel, Katelin B, Olsen, Margaret A, Wallace, Anna E, Warren, David K   +4 more
core   +2 more sources

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Penicillin Allergy: The Impact of a False Diagnosis

Acta Médica Portuguesa, 2019
N/a.
Bárbara Kong Cardoso, Sofia Martins Farinha, Marta Martins, Bárbara Lobão, Elza Tomaz, Filipe Inácio   +5 more
doaj   +1 more source

Characteristics of demand for antibiotics in primary care: an almost ideal demand system approach [PDF]

We model demand for different classes of antibiotics used for respiratory infections in outpatient care using a linear approximate almost ideal demand system approach.
Giuliano Masiero, Karine Moschetti, Massimo Filippini   +2 more
core  

Antibiotic resistance in the environment, with particular reference to MRSA [PDF]

, 2008
The introduction of β-lactam antibiotics (penicillins and cephalosporins) in the 1940s and 1950s probably represents the most dramatic event in the battle against infection in human medicine.
Aarestrup, Abraham, Agerso, Agustía, Anthonisen, Archer, Armand‐Lefevre, Asensio, Aubry‐Damon, Baptiste, Bass, Berg, Berghash, Bernabé, Biberstein, Boag, Bonnet, Boxall, Boyle‐Vavra, Briggs, Brinas, Brinas, Brinas, Burd, Burd, Burrus, Busato, Cefai, Chapin, Chee‐Sanford, Chen, Coello, Coffey, Couto, Couto, Cove, Dar, Daum, Davidson, De Liguoro, de Neeling, De Oliveira, Decousser, Devriese, Dingwell, Dunny, Eady, Ensor, Erskine, Fanaro, Fluit, Fox, Freter, Gaze, Gentilini, Germida, Gibbs, Gill, Golet, Gotz, Griggs, Guler, Halbert, Hall, Hamscher, Hansen‐Nord, Hanssen, Hanssen, Hardy, Hartman, Hasman, Hawes, Hawkey, Henriques, Herold, Heuer, Heuer, Hiramatsu, Hoekstra, Hollander, Holmes, Huijsdens, Hutchison, Ito, Ito, Jensen, Kapur, Katayama, Kirby, Kloos, Kummerer, Kuroda, Lee, Lee, Leverstein‐van Hall, Levy, Levy, Lilenbaum, Lindsay, Livermore, Lopes, Machado, Mahamoud, Manian, Marangon, McDonnell, Menzies, Mesa, Morales, Nandi, Neely, Nemergut, Nield, Nordmann, Owen, Owens, Partridge, Patel, Paulsen, Peacock, Pengov, Piddock, Piddock, Pirnay, Poirel, Poirel, Poirel, Poirel, Rahme, Raviglione, Recchia, Roberson, Robicsek, Rodriguez, Sapkota, Sasatsu, Sato, Sato, Segal, Seguin, Shea, Shiraki, Shukla, Sidhu, Sidhu, Singer, Smalla, Smit, Smith, Sorum, Stokes, Tennstedt, Tiemersma, Tikofsky, Tomlin, Top, Turtura, Turutoglu, van Den Bogaard, van den Bogaard, van Duijkeren, van Duijkeren, Vengust, Voss, Waldron, Weese, Weese, Weese, Weigel, White, Witte, Witte   +171 more
core   +1 more source