Results 11 to 20 of about 70,893 (311)
Documented penicillin allergies have been associated with an increased risk of adverse outcomes. The goal of this project was to assess the effectiveness and feasibility of a pharmacist-led penicillin allergy “de-labeling” process that does not involve ...
You-Chan Song +3 more
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Delabelling multiple antibiotic allergy: Practical issues
With the growing incidence of multi-drug resistant organisms, delabelling incorrect antibiotic allergies has become an integral part of antimicrobial stewardship worldwide.
Philip Hei Li, Bernard Yu-Hor Thong
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In clinical microbiology, matrix-assisted laser desorption ionization–time-of-flight mass spectrometry (MALDI-TOF MS) is frequently employed for rapid microbial identification.
Chia-Ru Chung +6 more
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Pitfalls in the Immunochemical Determination of β-Lactam Antibiotics in Water
Contamination of waters with pharmaceuticals is an alarming problem as it may support the evolution of antimicrobial resistance. Therefore, fast and cost-effective analytical methods for potential on-site analysis are desired in order to control the ...
Alexander Ecke, Rudolf J. Schneider
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The rate of invasive group B Streptococcus (GBS) infections is steadily increasing, particularly in older persons and in adults with diabetes and other comorbidities.
Corinne Ruppen +8 more
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History of penicillin: Beyond heroes, a social construction
The scientific breakthroug we know as “penicillin”, has been traditionally considered as the result of the genius of Alexander Fleming, awarded with the Nobel Prize for the discovery of the “miracle drug”.
Nicolás Giraldo-Hoyos
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β-lactam antibiotics (BLs) are the drugs most frequently involved in drug hypersensitivity reactions. However, current in vitro diagnostic tests have limited sensitivity, partly due to a poor understanding of in vivo drug–protein conjugates that both ...
Violeta Gil-Ocaña +19 more
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Introduction: Penicillin allergy labels (PAL) are common in the hospital setting and are associated with worse clinical outcomes. Desensitization can be a useful strategy for allergic patients when alternative options are suboptimal or not available. The
Alicia Rodríguez-Alarcón +19 more
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Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review
Background: β-lactams remain the cornerstone of the empirical therapy to treat various bacterial infections. This systematic review aimed to analyze the data describing the dosing regimen of β-lactams.Methods: Systematic scientific and grey literature ...
Abdul Haseeb +18 more
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