Results 31 to 40 of about 204,146 (354)
Frontiers in Immunology, 2021 β-lactam antibiotics (BLs) are the drugs most frequently involved in drug hypersensitivity reactions. However, current in vitro diagnostic tests have limited sensitivity, partly due to a poor understanding of in vivo drug–protein conjugates that both ...
Violeta Gil-Ocaña +19 more
doaj +1 more source
Cefazolin versus anti-staphylococcal penicillins for treatment of methicillin-susceptible Staphylococcus aureus bacteraemia: a narrative review [PDF]
Clinical Microbiology and Infection, Wiley, 2017, 2017 Anti-staphylococcal penicillins (ASPs) are recommended as first-line agents in methicillin-susceptible Staphylococcus aureus (MSSA) bacteraemia. Concerns about their safety profile have contributed to the increased use of cefazolin. The comparative clinical effectiveness and safety profile of cefazolin versus ASPs for such infections remain unclear ...
arxiv +1 more source
Dose optimization of β-lactams antibiotics in pediatrics and adults: A systematic review
Frontiers in Pharmacology, 2022 Background: β-lactams remain the cornerstone of the empirical therapy to treat various bacterial infections. This systematic review aimed to analyze the data describing the dosing regimen of β-lactams.Methods: Systematic scientific and grey literature ...
Abdul Haseeb +18 more
doaj +1 more source
SIAIP position paper: provocation challenge to antibiotics and non-steroidal anti-inflammatory drugs in children [PDF]
, 2018 Drug hypersensitivity reactions (DHRs) in childhood are mainly caused by betalactam or non-betalactam antibiotics, and non-steroidal anti-inflammatory drugs (NSAIDs).
Arasi, Stefania +19 more
core +1 more source
Broad-spectrum β-lactamases among Enterobacteriaceae of animal origin: molecular aspects, mobility and impact on public health [PDF]
, 2010 Broad-spectrum β-lactamase genes (coding for extended-spectrum β-lactamases (ESBLs) and AmpC β-lactamases) have been frequently demonstrated in the microbiota of food-producing animals. This may pose a human health hazard since these genes may be present
Butaye, Patrick +7 more
core +1 more source
ANTIBACTERIAL THERAPY OF INFECTIVE ENDOCARDITIS
Alʹmanah Kliničeskoj Mediciny, 2016 The article analyzes the influence of infective endocarditis etiology on the clinical course of the disease. The role of Staphylococci as common pathogens is emphasized. Streptococci have faded in importance, though, streptococcal endocarditis is still a
M. A. Gurevich, N. A. Kuz’menko
doaj +1 more source
Clinical Infectious Diseases, 2014 BACKGROUND Cross-reactivity between penicillins or cephalosporins and carbapenems is anticipated as all have a beta lactam ring. However, the true incidence of immunoglobulin (Ig)E-mediated cross-reactivity is not known. METHODS A systematic review was
B. Kula +2 more
semanticscholar +1 more source
History of penicillin: Beyond heroes, a social construction
Iatreia, 2021 The scientific breakthroug we know as “penicillin”, has been traditionally considered as the result of the genius of Alexander Fleming, awarded with the Nobel Prize for the discovery of the “miracle drug”.
Nicolás Giraldo-Hoyos
doaj +1 more source
Medication Errors Associated with the Use of Penicillins [PDF]
Клиническая микробиология и антимикробная химиотерапия, 2016 Objective. To determine the prevalence of medication errors associated with the use of penicillin-group antibiotics through analysis of national spontaneous reporting database. Materials and Methods. The study involved examination of 1123 spontaneous
Kuzmina A.V. +3 more
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