Results 161 to 170 of about 3,009,633 (302)

Daraxonrasib and Beyond: Pan‐RAS Inhibition, Resistance, and Next‐Generation Strategies

open access: yesCancer Science, EarlyView.
ABSTRACT RAS proteins have long been considered difficult therapeutic targets, but allele‐selective inhibitors established the clinical tractability of mutant RAS. Daraxonrasib (RMC‐6236), an oral pan‐RAS inhibitor, has now extended this concept by targeting multiple mutant and wild‐type RAS proteins.
Ryo Honda
wiley   +1 more source

Input Visualizations to Track Health Data by Older Adults with Multiple Chronic Conditions

open access: yesComputer Graphics Forum, EarlyView.
Abstract Older adults living with multiple chronic conditions (MCC) can considerably benefit from collecting and reflecting on their health data. Many older adults collect their health data using various approaches, such as digital tools or handwritten notebooks.
Shri Harini Ramesh   +4 more
wiley   +1 more source

Venous thromboembolism after penile cancer surgery: a UK PeCaN study. [PDF]

open access: yesBJU Int
Kaur A   +25 more
europepmc   +1 more source

Neoadjuvant Treatment for Penile Cancer: A Systematic Review of Contemporary Evidence. [PDF]

open access: yesCancers (Basel)
Santucci J   +7 more
europepmc   +1 more source

Representation of melanoma depth staging with limited central section sampling: a retrospective simulation study

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and Objectives For thick melanomas, retaining the primary lesion during neoadjuvant therapy may enhance immune response through increased antigen load. This study assessed whether a central section from serially processed melanoma specimen, representing a transectional incisional biopsy, accurately reflects Breslow thickness and ...
Katharina Pustelnik, Philipp Tschandl
wiley   +1 more source

Organ-sparing radiotherapy in penile cancer: therapeutic approaches. [PDF]

open access: yesInt Urol Nephrol
Muresan A   +6 more
europepmc   +1 more source

Economic Burden of Overweight and Obesity in Sweden: Current Estimates and Future Projections

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Overweight and obesity are major public health challenges and well‐established risk factors for cardiovascular disease, cancer and premature mortality. We estimated the economic burden of overweight and obesity in Sweden in 2023 and projected the future economic burden in 2040 under alternative scenarios of increasing prevalence ...
Adam Fridhammar   +5 more
wiley   +1 more source

Unveiling the variations in penile cancer care: identifying knowledge gaps and research priorities. [PDF]

open access: yesBMJ Oncol
Prakash G   +8 more
europepmc   +1 more source

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