Results 161 to 170 of about 173,582 (269)

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Successful Treatment of Cryptogenic NORSE Resistant to Immunosuppression With Intravenous Ganaxolone and Electroconvulsive Therapy. [PDF]

Neurohospitalist
Lan ZD, Malhotra R, Naqvi A, Barra M, Vaitkevicius H, Migdady I.   +5 more
europepmc   +1 more source

Epilepsy surgery: From bench to the clinics

Epilepsia Open, EarlyView.
Abstract Objective Recent advances in epilepsy surgery in patients with intractable epilepsy make it possible to study the mechanism of epilepsy in human brains. However, the true extent and propagation of each epileptogenic area from the epileptogenic focus in each patient is still difficult to perform “epilepsy cure” by surgery.
Tatsuya Tanaka
wiley   +1 more source

Efficacy of Intravenous Ketamine in Status Epilepticus: A Systematic Review and Meta-Analysis With Pediatric Subgroup Analysis. [PDF]

Cureus
Aldhafeeri BF, Alkhaldi O, Alajmi F, Alenezi L, Alajmi S, Alenezi E, Almotawtah S, Alenezi AM, Alnakkas Z, Alqallaf J, Altammar F.   +10 more
europepmc   +1 more source

CARDIAC TRANSPLANTATION IN THE RAT [PDF]

, 1989
CHAPMAN, FRANCES A, CRAMER, DONALD V, ESTES, LARRY W, HARNAHA, JO, MAKOWKA, LEONARD, QIAN, SHIQUANG, STARZL, THOMAS E   +6 more
core   +1 more source

Neonatal seizures and GABAergic drugs: Scylla and Charybdis?

Epilepsia Open, EarlyView.
Abstract Neonates have a high incidence of seizures that are frequently difficult to control with conventional first‐line anti‐seizure medications, which are gamma‐aminobutyric acid (GABA) agonists. The reasons for this clinical problem are multifold but are likely related to the unique physiology of the immature nervous system. Specifically, the early
Kerry W. Thompson, Lucie Suchomelova, Claude G. Wasterlain   +2 more
wiley   +1 more source

Survival after fatal pentobarbital ingestion

Indian Journal of Anaesthesia, 2014
Vinodkumar Singh
doaj   +1 more source

The Development and Optimisation of a Spinosin Solid-Dispersion-Based Functional Dairy Beverage and Its Sleep-Promoting Effects in Mice. [PDF]

Foods
Zhang B, Xie F, Chen N, Zhang Q, Zhao D, Chen Y, Xuan S, Liu X, Zhang L.   +8 more
europepmc   +1 more source

Peptide RL‐QN15 Regulates Functions of Epidermal Stem Cells to Accelerate Skin Wound Regeneration via the FZD8/β‐Catenin Axis

Exploration, EarlyView.
Amphibian‐derived peptide RL‐QN15 activates the Wnt/β‐catenin signaling pathway by interacting with the FZD8 membrane receptor, promoting epidermal stem cells proliferation, migration, stemness, and EMT processes, thus promoting skin wound healing.
Yuansheng Li, Qiuye Jia, Naixin Liu, Saige Yin, Junyuan Wang, Yujing Ding, Yuliu Yang, Ying Peng, Zeqiong Ru, Shaoyang Zhang, Bu'er Qi, Jun Sun, Li He, Ying Wang, Kun Guo, Xinwang Yang   +15 more
wiley   +1 more source

Propofol exerted the neuroprotective effects by regulating renin-angiotensin system and mitochondria-associated endoplasmic reticulum membrane in the postoperative cognitive dysfunction. [PDF]

BMC Anesthesiol
Ding W, Zheng Y, Li X, Lv H, Zhang J, Chen W.   +5 more
europepmc   +1 more source