Results 111 to 120 of about 129,200 (329)

Energy metabolism, adenosine, and glutamate signaling reprogramming by decanoic acid in Glut1 disorder syndrome

Epilepsia Open, EarlyView.
Abstract Glut1 deficiency syndrome (Glut1DS) leads to neurological and cognitive symptoms and is primarily treated using carbohydrate‐restricted ketogenic diets. However, a recent clinical trial of a less restrictive, non‐ketogenic, medium chain triglyceride (MCT) diet with a high decanoic acid content suggests efficacy in Glut1DS treatment.
Erwann Pain, Yatra Kapatel, Pankaj K. Singh, Katie Lloyd Jones, Jamuna Selvakumaran, Alberto Malerba, Walter Lucchesi, Tricia Rutherford, Christina A. Gurnett, Matthew C. Walker, Robin S. B. Williams   +10 more
wiley   +1 more source

Towards biogas production from vinasse and pentose liquor from sugarcane biorefineries

Energy Conversion and Management: X
Vinasse and pentose liquor are liquid streams produced as waste in sugarcane mills. Biogas production from these streams offers significant potential for energy recovery, contributing to sustainability and reducing fossil fuel dependency.
Diego Rafael Mágero Elihimas, Graciano Fernandes de Mendonça, Cláudia Jéssica da Silva Cavalcanti, Mauro Antonio da Silva Sa Ravagnani, Caliane Bastos Borba Costa, Diogo Ardaillon Simões, Sávia Gavazza, Bruna Soares Fernandes   +7 more
doaj   +1 more source

Heterologous xylose isomerase pathway and evolutionary engineering improve xylose utilization in Saccharomyces cerevisiae

Frontiers in Microbiology, 2015
Xylose utilization is one key issue for the bioconversion of lignocelluloses. It is promising approach to engineer heterologous pathway for xylose utilization in Saccharomyces cerevisiae.
Xin eQi, Jian eZha, Gao-Gang eLiu, Weiwen eZhang, Bing-Zhi eLi, Yingjin eYuan   +5 more
doaj   +1 more source

Development of a selection system for the detection of L-ribose isomerase expressing mutants of Escherichia coli [PDF]

, 2007
L-Arabinose isomerase (E.C. 5.3.1.14) catalyzes the reversible isomerization between L-arabinose and L-ribulose and is highly selective towards L-arabinose.
Beauprez, Joeri, De Maeseneire, Sofie, De Mey, Marjan, De Muynck, Cassandra, Soetaert, Wim, Van Bogaert, Inge, Van der Borght, Jef, Vandamme, Erick   +7 more
core   +1 more source

Pentose Metabolism in Saccharomyces cerevisiae: The Need to Engineer Global Regulatory Systems

Biotechnology Journal, 2018
Extending the host substrate range of industrially relevant microbes, such as Saccharomyces cerevisiae, has been a highly‐active area of research since the conception of metabolic engineering.
Venkatesh Endalur Gopinarayanan, Nikhil U. Nair   +1 more
semanticscholar   +1 more source

Exercise‐specific plasma proteomic signatures in racehorses: Candidates for training adaptation and peak load monitoring

Equine Veterinary Journal, EarlyView.
Abstract Background Racehorses undergo profound physiological changes with training and competition, but current biomarkers inadequately capture the complex molecular dynamics of exercise. This study aimed to identify novel plasma biomarkers of training adaptation and peak load using high‐throughput proteomics.
Jowita Grzędzicka, Bianka Świderska, Ewa Sitkiewicz, Izabela Dąbrowska, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

The ability of pentose pathways to form all essential metabolites provides clues to the origins of metabolism.

PLoS Biology
The structure of the early metabolic network is unknown. Here, we report that when considered together, pentose utilization pathways form all life-essential precursors.
Steffen N Lindner, Markus Ralser
doaj   +1 more source

Metabolic Dependencies in Pancreatic Cancer. [PDF]

, 2018
Pancreatic ductal adenocarcinoma (PDA) is a highly lethal cancer with a long-term survival rate under 10%. Available cytotoxic chemotherapies have significant side effects, and only marginal therapeutic efficacy. FDA approved drugs currently used against
Brody, Jonathan R., Vaziri-Gohar, Ali, Winter, Jordan M., Zarei, Mahsa   +3 more
core   +1 more source

Cuproptosis‐Related Genes in Immune Infiltration and Diagnosis in Hepatitis B Virus‐Related Acute Liver Failure

Exploration, EarlyView.
The role of cuproptosis in HBV‐ALF was explored via bioinformatics and liver biopsy tissues. There are some crosstalks among cuproptosis, immune infiltration, and ferroptosis (The figure was created by Bio Render). ABSTRACT Hepatitis B virus (HBV) infection poses a significant challenge to global health, particularly in developing countries such as ...
Jingwen Deng, Tao Zhu, Yueyang Wang, Sitong Zhang, Hong Deng, Guilan Quan, Tingting Peng, Chuanbin Wu, Huiqiang Cai, Chao Lu, Xiaopeng Cai   +10 more
wiley   +1 more source

Nontargeted metabonomics analysis of Scorias spongiosa fruiting bodies at different growth stages

Frontiers in Microbiology
IntroductionScorias spongiosa is an edible fungus.MethodsIn this study, a nontargeted metabonomic analysis was conducted on the fruiting bodies of this fungus at five growth stages, and the differences in metabolites and the related metabolic pathways ...
Xiang Nong, Xiang Nong, Xiang Nong, Xiang Nong, Shengnan Zhong, Lanying Huang, Lanying Huang, Lanying Huang, Lanying Huang, Jie Xiao, Ye Hu, Ye Hu, Ye Hu, Ye Hu, Yue Xie   +14 more
doaj   +1 more source