Results 91 to 100 of about 62,692 (265)
Safety Science and Technology, EarlyView.ABSTRACT Advanced biofuels derived from nonfood biomass are increasingly recognized as strategic components of low‐carbon energy systems, particularly for sectors where direct electrification remains difficult. Second‐generation biofuels from lignocellulosic residues and third‐generation biofuels from algal and aquatic biomass offer complementary ...
Majid Saidi, Amirreza Ahmadbozorgi
wiley +1 more source
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Insect Science, EarlyView.Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum
Insect Science, EarlyView.RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li +8 more
wiley +1 more source
Integrative Zoology, EarlyView.We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley +1 more source
Integrative Zoology, EarlyView.This study assessed the probiotic potential of intestinal microbiomes from five snake species using metagenomics and in vitro isolation, identifying two promising strains (Lactobacillus johnsonii DA0116 and Limosilactobacillus reuteri DA0218) through comprehensive screening.
Xuena Kang +11 more
wiley +1 more source
scMetaTraj: A Metabolism‐Centered Framework for Trajectory Inference in Single‐Cell Data
Med Research, EarlyView.
Jinwei Dai +5 more
wiley +1 more source
Integrative Zoology, EarlyView.A total of 435 non‐redundant metagenome‐assembled genomes (MAGs) were obtained from fecal samples of Taihangshan macaque across all four seasons. The alpha diversity of the gut microbiome in spring and winter was significantly higher than in summer and autumn. Furthermore, marked differences were detected in functional pathways and carbohydrate enzymes
Yanyan Zhou +6 more
wiley +1 more source
Methaemoglobinaemia: From pathophysiology to contemporary clinical management
British Journal of Haematology, EarlyView.Summary Methaemoglobin (MetHb) is an oxidised form of haemoglobin (Hb) unable to bind oxygen. Raised levels of MetHb reduce the blood's oxygen‐carrying capacity, causing potentially severe hypoxaemia and possible death. The condition arises from three main pathologies: mutations in globin genes causing Haemoglobin‐M, inherited deficiency of the enzyme ...
Alexander J. Twine, David C. Rees
wiley +1 more source
Cancer Science, EarlyView.Chemically modified siR‐PTBP1 disrupts the Warburg effect by reprogramming pyruvate kinase splicing from PKM2 to PKM1. This metabolic shift activates the TCA cycle, increases ATP production, and excessive ROS generation, and ultimately induces apoptotic cell death in colorectal cancer cells.
Keita Matsumoto +19 more
wiley +1 more source