Results 81 to 90 of about 99,088 (315)

Laboratory and greenhouse assessment of plant availability of organic N in animal manure [PDF]

, 2009
Laboratory data (thermal fractionation, pepsin extraction, C:No ratio) of dung and manure were mutually compared and contrasted with plant-availability of organic N (No) as found in a greenhouse experiment according to the double-pot technique. Two types
Antil, R.S., Janssen, B.H., Lantinga, E.A.   +2 more
core   +2 more sources

Acetylation Regulates ACSL4 Degradation Through Chaperone‐Mediated Autophagy to Alleviate Intervertebral Disc Degeneration

Advanced Science, EarlyView.
Intervertebral disc degeneration is triggered by ACSL4 accumulation‐mediated ferroptosis of nucleus pulposus cells due to CMA dysfunction. KAT2B promotes ACSL4 degradation via CMA through acetylation. AAV‐mediated LAMP2A delivery or engineered exosomes rescue nucleus pulposus cell senescence and disc degeneration.
Zhouwei Wu, Zhichen Jiang, Chenglong Hong, Shu Yang, Shuqing Jin, Chenyu Wu, Kaijie Guo, Jiang Liu, Shaobo Xu, Chenggui Wang, Xiangyang Wang   +10 more
wiley   +1 more source

Role of nitrite, urate and pepsin in the gastroprotective effects of saliva

Redox Biology, 2016
Dietary nitrate is now recognized as an alternative substrate for nitric oxide (•NO) production in the gut. This novel pathway implies the sequential reduction of nitrate to nitrite, •NO and other bioactive nitrogen oxides but the physiological relevance
Bárbara S. Rocha, Jon O Lundberg, Rafael Radi, João Laranjinha   +3 more
doaj   +1 more source

A Radial Diffusion Assay for Pepsinogen and Pepsin

Gastroenterology, 1969
A radial diffusion assay for the determination of gastric pepsin and uropepsin is developed. Urine, gastric juice, or solutions of hog pepsinogen are allowed to diffuse radially from circular wells in agar gel which contains acid-hemoglobin. After a period of incubation, the undigested hemoglobin is fixed with acid-alcohol, and after drying, the agar ...
I M, Samloff, M S, Kleinman
openaire   +2 more sources

SLPI⁺ AT2‐Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche

Advanced Science, EarlyView.
Integrating spatial transcriptomics and single‐cell RNA sequencing, this study identifies a novel subpopulation of SLPI⁺ AT2‐like cells at the invasive margin of lung adenocarcinoma (LUAD). These cells, through stromal crosstalk and Wnt pathway activation, promote tumor stemness and invasion.
Zhoufeng Wang, Guonian Zhu, Pan Tang, Yan Wang, Wenxin Luo, Wenpeng Song, Zhikang Pan, Bingjie Zheng, YongChao Jiang, Defu Xiao, Xin Jin, Yong Bai, Guowei Che, Weimin Li   +13 more
wiley   +1 more source

A Spectrophotometric Method for the Analysis of Pepsin

Gastroenterology, 1970
p-Nitrophenyl sulfite was found to be a suitable synthetic substrate for rapid spectrophotometric analysis of pepsin in gastric secretion. When this substrate was incubated with enzyme, the maximal rate of change of absorbance at 320 nm was found to be directly proportional to enzyme concentration.
L A, Robinson, T T, White
openaire   +2 more sources

Thyroxine is the serum factor that regulates morphogenesis of columnar cartilage from isolated chondrocytes in chemically defined medium. [PDF]

, 1994
Epiphyseal chondrocytes cultured in a medium containing 10% serum may be maintained as three dimensional aggregates and differentiate terminally into hypertrophic cells.
Ballock, RT, Reddi, AH
core  

On the selection and design of proteins and peptide derivatives for the production of photoluminescent, red-emitting gold quantum clusters [PDF]

, 2013
Novel pathways of the synthesis of photoluminescent gold quantum clusters (AuQCs) using biomolecules as reactants provide biocompatible products for biological imaging techniques.
A Baksi, A Harriman, A Retnakumari, AM Smith, BĐ Glišić, BĐ Glišić, C Giulivi, CAJ Lin, CAJ Lin, CF Shaw III, CL Liu, CV Durgadas, D Toroz, DM Chevrier, F Wen, G Mező, GA Simms, GS Harms, H Kawasaki, H Kawasaki, H Schmidbaur, H Tsunoyama, H Wei, J Xie, J Xie, JS Mohanty, K Chaudhari, L Shang, L Shang, M Zhu, MAH Muhammed, MAH Muhammed, MS Devadas, PK Xavier, PL Xavier, R Hamouda, S Link, S Si, TH Chen, X Wen, X Yuan, X Yuan, XL Guével, Y Negishi, Y Shichibu, Y Shichibu, Y Wang, YH Lin, YN Tan   +48 more
core   +2 more sources

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

Advanced Science, EarlyView.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee, Jeongho Lee, Min‐Seo Choi, Minjun Ahn, Sik Yoon, Dongjun Lee, Sae‐Ock Oh, Won‐Woo Cho, Byoung Soo Kim   +8 more
wiley   +1 more source

Leucine‐Dependent SLC7A5–PGAM5 Interaction Promotes Advanced Atherosclerosis Through Hindering Mitochondrial Function of Macrophages

Advanced Science, EarlyView.
Higher plasma leucine is associated with increased risk of new‐onset myocardial infarction. Leucine deprivation alleviates advanced atherosclerosis in mice. Tumor‐induced leucine deprivation reprograms macrophage metabolism and increases CD5Lhi macrophages in mouse plaques. Mechanistically, leucine deficiency reduced SLC7A5‐PGAM5 binding in macrophages,
Shan Zhong, Xueyu Wang, Qingsong Li, Siqi Wang, Bin Sun, Wenjun Ni, Gengyu Zhou, Fan Wang, Xianwei Xie, Cheng Jin, Gang Xu, Peng Zhao, Xiang Peng, Feiyuan Han, Xiangwen Xi, Yidan Wang, Juan Xu, Yue Wang, Xia Gu, Shuo Li, Jian Zhang, Shuijie Li, Jinwei Tian   +22 more
wiley   +1 more source