Results 81 to 90 of about 1,324 (208)

Gastric cancer, cytotoxin - associated Gene-A positive helicobacter pylori and serum pepsinogens: an international study

, 1999
Background & Aims: CagA-positive Helicobacter pylori infection has been more closely associated with gastric disease than CagA-negative infection. This study evaluated whether geographic variation in the prevalence of CagA could explain variation in ...
FORMAN, D, Webb, P. M., WEBB, PM, CRABTREE, JE, Eurogast Study Group, Forman, D., Crabtree, J. E.   +6 more
core   +1 more source

Maternal serum pepsinogen-1 levels in severe hyperemesis gravidarum and the need for hospitalization: a prospective study

BMC Pregnancy and Childbirth
Background We aimed to examine whether there is a statistical difference in maternal serum pepsinogen-1 (MSPG-1) between pregnant women with severe hyperemesis gravidarum (HG) and those with moderate HG managed without hospitalization and to explore an ...
Sadun Sucu, Fahri Burcin Firatligil, Ahmet Kurt, Murat Levent Dereli, Ramazan Erda Pay, Sadullah Ozkan   +5 more
doaj   +1 more source

Gastric Cancer Screening by Combined Determination of Serum Helicobacter pylori Antibody and Pepsinogen Concentrations: ABC Method for Gastric Cancer Screening

Chinese Medical Journal, 2018
Objective: Gastroscopy combined with gastric mucosa biopsies is currently regarded as a gold standard for diagnosis of gastric cancer. However, its application is restricted in clinical practice due to its invasive property.
Xian-Zhe Chen, Cheng-Zhi Huang, Wei-Xian Hu, Ying Liu, Xue-Qing Yao   +4 more
doaj   +1 more source

Asiatic Acid Ameliorates MNNG‐Induced Chronic Atrophic Gastritis by Inhibiting the Activation of the HRAS/PI3K/AKT/GSK3β Signaling Axis

Phytotherapy Research, Volume 40, Issue 5, Page 2210-2229, May 2026.
ABSTRACT Chronic atrophic gastritis (CAG), a widespread gastrointestinal condition, is widely acknowledged as a precursor to gastric cancer (GC). The incidence of CAG has been steadily increasing, yet effective pharmacological interventions remain unavailable.
Feifei Zhou, Cuiyu Zhu, Wanwan Yuan, Wenkun Peng, Qianqian Xu, Hongli Yang, Ruofan Cao, Ben Wang, Meiqian Wang, Hongwei Xu   +9 more
wiley   +1 more source

Serum pepsinogens can help to discriminate between H. pylori-induced and auto-immune atrophic gastritis: Results from a prospective multicenter study

, 2023
International audienceBackground: Serum pepsinogen (PG) testing is recommended by the European guidelines for diagnosis of chronic atrophic gastritis (CAG).
Martin, Jérôme, Osmola, Malgorzata, Vibet, Marie-Anne, Leroy, Maxime, Blin, Justine, Matysiak-Budnik, Tamara, Bigot-Corbel, Edith, Chapelle, Nicolas, Hémont, Caroline, Moussata, Driffa, Masson, Damien, Lamarque, Dominique, Tougeron, David, Josien, Régis, Mosnier, Jean-François   +14 more
core   +1 more source

The proteomic differences and expression of fatty acid‐binding protein 6 (FABP6) associated with gastrointestinal injury in horses with oral administration of a clinical dose of phenylbutazone

Equine Veterinary Journal, Volume 58, Issue 3, Page 845-856, May 2026.
Abstract Background Phenylbutazone (PBZ) can potentially induce gastrointestinal ulceration, and early detection of PBZ‐induced gastroenteropathy will be useful for the diagnosis, treatment, and prevention of PBZ toxicity. Objectives To identify putative proteins associated with equine gastric ulcer syndrome after clinical dose (4.4 mg/kg ...
Ruethaiwan Vinijkumthorn, Nawarus Prapaiwan, Thanapon Chotikaprakal, Phirom Prompiram, Narumon Phaonakrop, Sittiruk Roytrakul, Parichart Tesena   +6 more
wiley   +1 more source

Are the Serum Biomarkers Pepsinogen I and II Good Predictors for the Detection of Subjects with Atrophic Gastritis in Areas that have Different Gastric Cancer Incidence. [PDF]

BACKGROUND: Northern Iran (Ardabil) is characterized by a high gastric cancer (GC) rate, whereas Southern Iran (Kerman and Yazd) has a low GC rate. The aim of this study is to verify the potential for pepsinogen I and II to detect atrophic gastritis ...
مسرت, صادق, سجادی, علیرضا, سلمانرخانی, حسن, حاج شیخ الاسلامی, ارغوان, محمدخانی, اشرف, علاف اصغری, امین, بشیری, جعفر, یزدانبد, عباس, درویش مقدم, صدیف, میرزایی, محبوبه   +9 more
core  

Acetylation of Pepsin and Pepsinogen

Journal of Biological Chemistry, 1966
Abstract 1. Acetylimidazole, an acetylating reagent of proteins reacts both with the proteolytic enzyme, pepsin, and its zymogen, pepsinogen. 2. When reacted with pepsin, the proteolytic activity decreases whereas the hydrolysis of the synthetic substrate, N-acetyl-dl-phenylalanyldiiodotyrosine, increases 2.5-fold.
openaire   +2 more sources

Serological markers as predictors of the severity of gastric mucosal atrophy in autoimmune and Helicobacter рylori-associated gastritis

Терапевтический архив
Aim. To evaluate the possibility of using serum markers of atrophy (pepsinogens – PG I and II) to form high-risk groups for gastric cancer (Operative Link for Gastritis Assessment – OLGA stage III–IV) depending on the etiology of gastritis.
Margarita V. Chebotareva, Karine A. Nikolskaya, Dmitry N. Andreev, Alexey S. Dorofeev, Sergey G. Khomeriki, Larisa A. Tsapkova, Elena V. Parfenchikova, Artur M. Veliev, Alexey Yu. Spasenov, Irina N. Voynovan, Dmitry S. Bordin   +10 more
doaj   +1 more source

Helicobacter pylori infection, serum pepsinogens as markers of atrophic gastritis, and leukocyte telomere length: a population-based study

Human Genomics, 2019
Background Persistent infections that induce prolonged inflammation might negatively affect the leukocyte telomere length (LTL); however, the role in LTL of Helicobacter pylori (H.
Khitam Muhsen, Ronit Sinnreich, Dafna Merom, Hisham Nassar, Dani Cohen, Jeremy D. Kark   +5 more
doaj   +1 more source