Results 151 to 160 of about 232,235 (310)
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels +7 morewiley +1 more sourcePromiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski +6 morewiley +1 more sourceMatrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells
FEBS Open Bio, EarlyView.Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek +8 morewiley +1 more sourceStructural and mechanistic insights into caseinolytic protease inhibition for antimicrobial development against Pseudomonas plecoglossicida. [PDF]
PLoS PathogChen J, Zhang P, Guan H, Gong B, Li X, Li Z, Li F, Zhou B, Chen X, Chen X, Ouyang S, Zhang YA. +11 moreeuropepmc +1 more sourceMitochondrial protein import [PDF]
, 1989 Ades, Ades, Adrian, Ainger, Allison, Alt, Aquila, Aquila, Arakawa, Arends, Argan, Argan, Baker, Banroques, Basile, Beckmann, Bedwell, Behra, Bellion, Beltzer, Beltzer, Berkhout, Bhasker, Bhat, Blobel, Borst, Bouillaud, Boutry, Brandriss, Braun, Burns, Böhni, Böhni, Cerletti, Chatton, Chen, Chen, Chen, Chen, Chen, Cheng, Chien, Chien, Chirico, Chu, Conboy, Conboy, Coruzzi, Craig, Dahl, Daum, Daum, De Haan, De Jong, De Lange, De Lange, Deshaies, Dickerson, Dieckmann, Dieckmann, Douglas, Duffaud, Dumont, Eilers, Eilers, Eilers, Ellis, Ellis, Emr, Epand, Evans, Farrell, Farrell, Faye, Firgaira, Fisher, Flügge, Foury, Fox, Freeman, Freitag, Fujiki, Fujiki, Gabellini, Gabellini, Gasser, Gasser, Gasser, Gay, Gearing, Geller, Gillespie, Gilmore, Gilmore, Grant, Grossmann, Guiard, Hackenbrock, Hallemayer, Hallermayer, Hallewell, Hampsey, Hansen, Harmey, Harmey, Harmey, Harmey, Harnisch, Hartl, Hartl, Hartl, Hartl, Hase, Hase, Hase, Hatalova, Hauska, Hawlitschek, Hay, Heinrich, Hemmingsen, Hennig, Hennig, Hennig, Henning, Hensgen, Ho, Ho, Horwich, Horwich, Horwich, Horwich, Horwich, Horwich, Hunter, Hurt, Hurt, Hurt, Hurt, Hurt, Hurt, Hurt, Hurt, Imanaka, Ito, Jaussi, Jaussi, Joh, Just, Kanazawa, Kaput, Kellems, Kellems, Kellens, Keng, Kirwin, Kleene, Koerner, Koerner, Koike, Kolansky, Kolarov, Korb, Kraus, Kraus, Kraus, Kraus, Krebs, Kruse, Kryzwicki, Kun, Labouesse, Lazarow, Lederer, Lennart-Nilsson, Lewin, Lewin, Lindquist, Lingelbach, Lomax, Lubben, Lustig, Lustig, Maarse, Maarse, Maccecchini, Maccecchini, Macino, Maher, Marres, Marzuki, Matsubara, Matsuura, McAda, McGraw, McIntyre, Meyer, Meyer, Meyer, Michel, Mihara, Mihara, Mihara, Mihara, Miura, Miura, Mori, Mori, Morita, Morohashi, Morohashi, Morohashi, Mueckler, Mueckler, Mueckler, Myers, Myers, Müller, Müller, Nagata, Nakagawa, Nargang, Natsoulis, Nelson, Nelson, Ness, Neupert, Neupert, Nguyen, Nguyen, Nguyen, Nguyen, Nicholson, Nicholson, Nicholson, Nicholson, Nishikimi, Nyunoya, Oda, Oda, Ohashi, Ohba, Ohba, Ohta, Ohta, Okamura, Okamura, Ono, Ono, Ono, Ono, Ou, Ou, Oudshoorn, Pain, Pain, Pape, Pape, Park, Patterson, Pelham, Perara, Pfaller, Pfaller, Pfaller, Pfaller, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pfanner, Pillar, Pollock, Pratje, Pratje, Randall, Randall, Raymond, Reid, Reid, Richter, Ricquier, Ridley, Rietveld, Riezman, Riezman, Riezman, Robinson, Roise, Roise, Rothblatt, Rothman, Runswick, Rödel, Römisch, Sabatini, Sachs, Sadler, Saraste, Schatz, Schlenstedt, Schleyer, Schleyer, Schleyer, Schmeizer, Schmidt, Schmidt, Schmidt, Schmidt, Schmidt, Schneller, Schwaiger, Schägger, Sebald, Shore, Sidhu, Sierra, Simmaco, Skerjank, Smagula, Stellwagen, Stuart, Suissa, Suissa, Surguchov, Suske, Sztul, Söllner, Takeda, Takeda, Takiguchi, Tamm, Taniuchi, Teintze, Tropschug, Tzagoloff, Tzagoloff, Ueda, Urban-Grimal, Van Loon, Van Loon, Van Loon, Van Loon, Van Loon, Van Loon, Van Loon, Van Loon, Van Steeg, Vasarotti, Vasarotti, Veloso, Velours, Verner, Vestweber, Viebrock, Von Heijne, Walter, Walter, Walter, Watanabe, Waters, Watts, Weiss, Werner, Wickner, Wiech, Wielburski, Wierenga, Witte, Wold, Woodrow, Wright, Wright, Wu, Yaffe, Yaffe, Yamane, Yoshida, Yoshida, Young, Zimmermann, Zimmermann, Zimmermann, Zimmermann, Zimmermann, Zimmermann, Zwizinski, Zwizinski, Zwizinski, Zwizinski +395 morecore +1 more source
