Regulated Inositol‐Requiring Protein 1‐Dependent Decay as a Mechanism of Corin RNA and Protein Deficiency in Advanced Human Systolic Heart Failure [PDF]
, 2014 BACKGROUND: The compensatory actions of the endogenous natriuretic peptide system require adequate processing of natriuretic peptide pro‐hormones into biologically active, carboxyl‐terminal fragments.
Barton, P +5 more
core +1 more source
The IkB kinase inhibitor nuclear factor-kB essential modulator–binding domain peptide for inhibition of balloon injury-induced neointimal formation [PDF]
, 2009 Objective—The activation of nuclear factor-kB (NF-kB) is a crucial step in the arterial wall’s response to injury. The identification and characterization of the NF-kB essential modulator– binding domain (NBD) peptide, which can block the activation of
Carnuccio, R. +12 more
core +1 more source
MSFragger: ultrafast and comprehensive peptide identification in shotgun proteomics
Nature Methods, 2017 There is a need to better understand and handle the 'dark matter' of proteomics—the vast diversity of post-translational and chemical modifications that are unaccounted in a typical mass spectrometry–based analysis and thus remain unidentified.
Andy T. Kong +4 more
semanticscholar +1 more source
APD3: the antimicrobial peptide database as a tool for research and education
Nucleic Acids Res., 2015 The antimicrobial peptide database (APD, http://aps.unmc.edu/AP/) is an original database initially online in 2003. The APD2 (2009 version) has been regularly updated and further expanded into the APD3.
Guangshun Wang, Xia Li, Zhe Wang
semanticscholar +1 more source
Candida albicans biofilm formation on peptide functionalized polydimethylsiloxane [PDF]
, 2010 In order to prevent biofilm formation by Candida albicans, several cationic peptides were covalently bound to polydimethylsiloxane (PDMS). The salivary peptide histatin 5 and two synthetic variants (Dhvar 4 and Dhvar 5) were used to prepare peptide ...
Coenye, Tom +7 more
core +1 more source
Catalytically active peptide–gold nanoparticle conjugates: Prospecting for artificial enzymes [PDF]
, 2020 The self‐assembly of peptides onto the surface of gold nanoparticles has emerged as a promising strategy towards the creation of artificial enzymes.
Berger, Allison A. +2 more
core +1 more source
Breast Cancer Research, 2023 Background Radiotherapy is widely applied in breast cancer treatment, while radiotherapy resistance is inevitable. TGF-β1 has been considered to be an endogenous factor for the development of radiotherapy resistance.
Fayun Zhang +7 more
doaj +1 more source
Crystal structure of methyl 1-(2-(fluorosulfonyl)ethyl)-2-oxocyclopentanecarboxylate, C9H13FO5S
Zeitschrift für Kristallographie - New Crystal Structures, 2017 C9H13FO5S, triclinic, P1̅ (no. 2), a = 5.9390(3) Å, b = 8.1581(4) Å, c = 11.3823(8) Å, α = 89.498(3)°, β = 85.314(5)°, γ = 84.916(5)°, V = 547.48(5) Å3, Z = 2, Rgt(F) = 0.0303, wRref(F2) = 0.0811, T = 293 K.
Govender Kimberleigh B. +4 more
doaj +1 more source
Hsc66 substrate specificity is directed toward a discrete region of the iron-sulfur cluster template protein IscU [PDF]
, 2002 Hsc66 and Hsc20 comprise a specialized chaperone system important for the assembly of iron-sulfur clusters in Escherchia coli. Only a single substrate, the Fe/S template protein IscU, has been identified for the Hsc66/Hsc20 system, but the mechanism by ...
Hoff, Kevin G. +4 more
core +1 more source
Crystal structure of (E)-2-(4-cyanophenyl)ethenesulfonyl fluoride, C9H6FNO2S
Zeitschrift für Kristallographie - New Crystal Structures, 2019 C9H6FNO2S, triclinic, P1̄ (no. 2), a = 7.2786(2) Å, b = 8.1014(3) Å, c = 16.1084(5) Å, α = 76.320(1)°, β = 87.918(1)°, γ = 80.784(1)°, V = 911.00(5) Å3, Z = 4, Rgt(F) = 0.0298, wRref(F2) = 0.0857, T = 100(2) K.
Brasil Edikarlos +4 more
doaj +1 more source