Results 41 to 50 of about 3,466,843 (390)
Cyclic homodimer formation by singlet oxygen-mediated oxidation of carnosine
Frontiers in ChemistryAlthough carnosine (β-Ala-L-His) is one of physiological protectants against in vivo damages caused by reactive oxygen species (ROS), its reactivity against singlet oxygen (1O2), an ROS, is still unclear at the molecular level.
Hiroko Kawakami +5 more
doaj +1 more source
SynOpen, 2018 Biologically attractive azaspiro[4.5]trienones have been prepared via Ugi four-component reaction (Ugi-4CR) followed by bromine-mediated ipso-cyclization.
Saeed Balalaie +5 more
doaj +1 more source
Antibiotics, 2023 Virulent Enterobacterale strains expressing serine and metallo-β-lactamases (MBL) genes have emerged responsible for conferring resistance to hard-to-treat infectious diseases. One strategy that exists is to develop β-lactamase inhibitors to counter this
Nakita Reddy +17 more
doaj +1 more source
Synthesis and cellular penetration properties of new phosphonium based cationic amphiphilic peptides [PDF]
, 2018 A new category of phosphonium based cationic amphiphilic peptides has been developed and evaluated as potential antimicrobial peptides and cell penetrating peptides.
Gannon, Susan +7 more
core +1 more source
eLife, 2018 Why does cancer develop in situations where the immune system is perfectly capable of eliminating it?
Jian Guan, Nilabh Shastri
openaire +4 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Zeitschrift für Kristallographie - New Crystal Structures, 2017 C68H72O10, triclinic, P1̅ (no. 2), a = 13.3619(4) Å, b = 13.9234(4) Å, c = 16.6975(5) Å, α = 96.023(2)°, β = 104.537(1)°, γ = 105.625(1)°, V = 2845.85(15) Å3, Z = 2, Rgt(F) = 0.0491, wRref(F2) = 0.1311, T = 173 K.
Samipillai Marivel +3 more
doaj +1 more source
A Comprehensive Review on Current Advances in Peptide Drug Development and Design
International Journal of Molecular Sciences, 2019 Protein–protein interactions (PPIs) execute many fundamental cellular functions and have served as prime drug targets over the last two decades. Interfering intracellular PPIs with small molecules has been extremely difficult for larger or flat binding ...
A. Lee +3 more
semanticscholar +1 more source
Peptide Bioinformatics- Peptide Classification Using Peptide Machines [PDF]
, 2008 Peptides scanned from whole protein sequences are the core information for many peptide bioinformatics research such as functional site prediction, protein structure identification, and protein function recognition. In these applications, we normally need to assign a peptide to one of the given categories using a computer model.
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Preferred Configurations of Peptide–Peptide Interactions
The Journal of Physical Chemistry A, 2013 The natural and fundamental proclivities of interaction between a pair of peptide units are examined using high-level ab initio calculations. The NH···O H-bonded structure is found to be the most stable configuration of the N-methylacetamide (NMA) model dimer, but only slightly more so than a stacked arrangement.
Adhikari, U., Scheiner, Steve
openaire +6 more sources