Results 151 to 160 of about 2,035,646 (256)

Emerging Technologies for Oral Peptide Delivery: From Bioinspired Systems to Smart Device-Assisted Drug Delivery. [PDF]

Pharmaceuticals (Basel)
Vasović S, Vasović L, Martić N, Chirasatitsin S, Vasović V, Vukmirović S, Pavlović N.   +6 more
europepmc   +1 more source

Re-Assessing PK/PD Issues for Oral Protein and Peptide Delivery. [PDF]

Pharmaceutics, 2021
Mrsny RJ, Mahmood TA.
europepmc   +1 more source

Ionizable Lipid‐Dependent Optimization of Steroid Lipid Nanoparticles With Tunable Immunomodulatory Properties

Advanced Materials, EarlyView.
A novel engineering strategy that establishes material design principles for incorporating anti‐inflammatory steroids into lipid nanoparticles to reduce LNP‐induced inflammation while retaining mRNA delivery. Results are validated in vitro and in three animal models of inflammation and autoimmunity in vivo.
Ajay S. Thatte, Benjamin E. Nachod, Julia Baena, Jenna Muscat‐Rivera, Lesley Chaboub, Hannah C. Safford, Hannah C. Geisler, Hannah M. Yamagata, Melgious J. Y. Ang, Michael Kegel, Alexandre Poirier, Elaine R. Tong, Zhe Zhong, Qiangqiang Shi, Jinjin Wang, Elisa Battistini, Ye Zeng, Alex G. Hamilton, Kelsey L. Swingle, Drew Weissman, Jilian R. Melamed, Michael J. Mitchell   +21 more
wiley   +1 more source

Self-assembling surfactant-like peptide A6K as potential delivery system for hydrophobic drugs

, 2015
Yongzhu Chen,1 Chengkang Tang,2 Jie Zhang,2 Meng Gong,3 Bo Su,2 Feng Qiu4 1Periodical Press, 2Core Facility of West China Hospital, 3Laboratory of Endocrinology and Metabolism, West China Hospital, 4Laboratory of Anaesthesia and Critical Care Medicine ...
Su B, Zhang J, Qiu F, Tang C, Gong M, Chen Y   +5 more
core  

Navigating the complexity of oral peptide delivery: challenges and strategies to enhance oral bioavailability. [PDF]

Front Drug Deliv
Khalid NU, Rivera-Delgado E, von Erlach T.   +2 more
europepmc   +1 more source

Dendrimeric HIV-peptide delivery nanosystem affects lipid membranes structure. [PDF]

Sci Rep, 2021
Milowska K, Rodacka A, Melikishvili S, Buczkowski A, Pałecz B, Waczulikova I, Hianik T, Majoral JP, Ionov M, Bryszewska M.   +9 more
europepmc   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Submicron-sized ultrasound contrast agents as therapeutic peptide delivery vehicles in type 1 diabetes. [PDF]

Theranostics
Ciccaglione M, Abenojar E, Kosmides T, DiLisio JE, McDaniel KA, Hartmoore K, Gresch A, Jarrell DK, Ramirez DG, Sticco-Ivins M, Michels AW, Haskins K, Exner AA, Benninger RKP.   +13 more
europepmc   +1 more source

S‐Nitrosothiols as Thiol‐Protecting Groups for Controlled Thiol‐Maleimide Crosslinking of Homogeneous Soft Hydrogels

Advanced Materials, EarlyView.
Rapid thiol‐maleimide addition frequently outpaces mixing, resulting in heterogeneous hydrogels. S‐nitrosothiols act as thiol‐protecting groups, allowing uniform mixing with maleimide‐functionalized polymers before gelation. Sodium thiosulfate or sodium ascorbate then regenerates thiols on demand, triggering controlled thiol‐maleimide crosslinking ...
Julian A. Serna, Michelle J. Iwohn, Maximilian Seifermann, Stefan Heißler, Maike Schliephake, Franziska Dopp, Claudia Muhle‐Goll, Pavel A. Levkin   +7 more
wiley   +1 more source

Overcoming Gastric Barriers for Oral Peptide Delivery: QbD-Based Development of Sodium Caprate-Enabled Tirzepatide Tablets. [PDF]

Pharmaceutics
Im S, Lee JY, Kim JE.
europepmc   +1 more source