Results 221 to 230 of about 995,438 (315)

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Engineering Linker-Enhanced OmpG Nanopores for Rapid Single-Molecule Protease Detection. [PDF]

Sensors (Basel)
Kim M, Pham B.
europepmc   +1 more source

Sex differences in the physiological response to acute anterior cruciate ligament overuse

The Journal of Physiology, EarlyView.
Abstract figure legend With equivalent in vivo fatigue loading of the anterior cruciate ligament (ACL), females accumulate more tissue damage and mount a slower reparative response than males, when the applied loads between sexes are equivalent. By contrast, males accumulate less tissue damage and mount a robust reparative response that includes ...
Stephen H. Schlecht, Benjamin E. Loflin, Adam R. Carter, Roufael Hanna, Simran Shergill, Edward M. Wojtys   +5 more
wiley   +1 more source

Temperature-dependent regulation of bacterial cell division hydrolases by the coordinated action of a regulatory RNA and the ClpXP protease. [PDF]

Cell Surf
Mebus VH, Busch LM, Børre M, Nielsen TK, Bojer MS, Henriksen C, Barbuti MD, Angeles DM, Brejndal K, Michalik S, Salazar MG, Kjos M, Völker U, Kallipolitis BH, Frees D.   +14 more
europepmc   +1 more source

Protein design and RNA design: Perspectives

Quantitative Biology, Volume 14, Issue 2, June 2026.
Abstract Advances in deep learning and generative modeling have transformed the landscape of protein and RNA design, enabling rapid and precise creation of novel biomolecules with tailored structures and functions. In protein design, generative deep learning frameworks now support backbone generation, sequence optimization, and joint sequence–structure
Xi Chen, Xu Dai, Peilong Lu
wiley   +1 more source

Identification and whole genome sequencing analysis of Bacillus subtilis K35-1, a highly efficient cellulose in forage degrading bacterium. [PDF]

BMC Microbiol
Wu D, Feng J, Wen D, Wang H, Lu S, Li K, Sultan R, Li B.   +7 more
europepmc   +1 more source

Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions

Traffic, Volume 27, Issue 1, March 2026.
Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang, Jingyi Fu, Shan Li, Zehui Li, Qirui Zhao, Yuqi Yin, Mei Yang, Yonghua Wang   +7 more
wiley   +1 more source

A Thermostable Bacterial Metallohydrolase that Degrades Organophosphate Plasticizers. [PDF]

Chembiochem
Ji D, Frkic RL, Delyami J, Larsen JS, Spence MA, Jackson CJ.   +5 more
europepmc   +1 more source

Regulating Promiscuous Catalysis via Substrate‐Induced Transient Assembly

Angewandte Chemie International Edition, Volume 65, Issue 1, 2 January 2026.
We report a novel substrate‐induced transient co‐assembly between a short Lys‐rich peptide and Fmoc‐Gly‐OH. In the activated state, the assembly exhibits promiscuous catalytic activity through the rate enhancements of hydrolysis and C═N condensation reactions.
Ayan Chatterjee, Maximilian Schuler, Marius G. Braun, Christopher V. Synatschke, Qi Lu, Jiyao Yu, David Y.W. Ng, Tanja Weil   +7 more
wiley   +1 more source

It Is Dangerous to Go Alone: Strategies to Optimize PET Biocatalysis and Upcycling through Enzymatic Synergism. [PDF]

ACS Omega
Dahmer BR, de Lima JC, Ruggiero Bachega JF, Wymore T, Saraiva Macedo Timmers LF.   +4 more
europepmc   +1 more source