Results 111 to 120 of about 134,053 (282)
Recent Advances in mRNA Delivery Systems for Cancer Therapy
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang+9 more
wiley +1 more source
Development of peptide nucleic acid-based bead array technology for Bacillus cereus detection. [PDF]
Noppakuadrittidej P+7 more
europepmc +1 more source
This review compares clinical outcomes, translational progress, and global funding trends across cancer phototherapies—photodynamic, photothermal, and photoimmunotherapy—and conventional immunotherapy. It highlights differences in treatment efficacy, clinical trial status, financial investment, and regulatory challenges, providing a comprehensive ...
Deepak S. Chauhan+6 more
wiley +1 more source
Advanced Pharmaceutical Nanotechnologies Applied for Chinese Herbal Medicines
This review offers a comprehensive overview of pharmaceutical nanotechnology strategies to address limitations associated with the complex material basis and relative mild therapeutic efficacy of Chinese herbal medicines, and summarizes the advantages of these strategies.
Jiameng Li+11 more
wiley +1 more source
A phosphorothioate‐modified aptamer PTf‐SRiApt capable of disrupting “undruggable” transcription factor SCAF4‐POLR2A interaction with high inhibitory activity and biological stability is presented here. Through this inhibition, PTf‐SRiApt successfully arrested cell cycle progression, induced cell death, and elevated immune recruitment in SCAF4‐POLR2A ...
Liyan Fei+13 more
wiley +1 more source
Triplex-Forming Peptide Nucleic Acid Controls Dynamic Conformations of RNA Bulges. [PDF]
Ryan CA, Rahman MM, Kumar V, Rozners E.
europepmc +1 more source
IPA is an intestinal tryptophan metabolite whose effects decline with decreased heart function. Supplementing IPA can alleviate the aging‐related myocardial fibrosis through PPT1. PPT1 is a key protein localized to lysosomes, and IPA can restore macrophage autophagy function by regulating PPT1 expresssions, thereby reducing aging‐related myocardial ...
Jing Lu+16 more
wiley +1 more source
Catalytic hairpin assembly‐propelled weak‐inputs‐strong‐outputs (CP‐WISO) DNA logic nanodevices with orthogonal design and contrary logic responses are innovatively fabricated. Moreover, the even and odd parity generators/checkers for ensuring normal molecular data transmission, and the logic‐programmed miRNA biosensors with ratiometric fluorescent ...
Xujuan Lv+8 more
wiley +1 more source