Results 121 to 130 of about 205,916 (160)

Peptide nucleic acids as therapeutic agents

Current Opinion in Structural Biology, 1999
Peptide nucleic acids (PNAs) have been around for more than seven years and it was hoped, at their introduction, that they would quickly enter the fields of antisense and antigene technology and drug development. Despite their extremely favorable hybridization and stability properties, as well as the encouraging antisense and antigene activity of PNA ...
openaire   +2 more sources

Peptide Nucleic Acids

2007
Peptide nucleic acids (PNAs) can be conveniently delivered into cells in complex with DNA and cationic lipid. This advance enables researchers to test the hypothesis that PNAs offer advantages for recognition of DNA or RNA targets within cells. In this review, I describe the intracellular delivery of PNAs as DNA-PNA-cationic lipid complexes and discuss
openaire   +1 more source

Automated Synthesis of Peptide Nucleic Acids and Peptide Nucleic Acid–Peptide Conjugates

Analytical Biochemistry, 1999
L D, Mayfield, D R, Corey
openaire   +2 more sources

Peptide Nucleic Acids and the Origin of Life

Chemistry & Biodiversity, 2007
AbstractThe possibilities of pseudo‐peptide‐DNA mimics like PNA (peptide nucleic acid) having a role for the prebiotic origin of life prior to an RNA world is discussed on the basis of literature data showing that this type of molecules might have formed on the primitive earth (or other places in the universe), as well as data indicating the ...
openaire   +3 more sources

Peptide nucleic acid and antifouling peptide based biosensor for the non-fouling detection of COVID-19 nucleic acid in saliva

Biosensors and Bioelectronics, 2023
Xiliang Luo, Zhenying Xu, Shuju Zhao
exaly  

Peptide Nucleic Acid (PNA)‐Guided Peptide Engineering of an Aptamer Sensor for Protease‐Triggered Molecular Imaging

Angewandte Chemie - International Edition, 2021
Lele Li, Jian Zhao, Zhenghan Di
exaly  

Head on Comparison of Self‐ and Nano‐Assemblies of Gamma Peptide Nucleic Acid Amphiphiles

Advanced Functional Materials, 2022
Raman Bahal, Kuo-Chih Shih, Mu-Ping Nieh   +2 more
exaly  

Chimeric Peptide-Based Biomolecular Constructs for Versatile Nucleic Acid Biosensing

ACS Applied Materials & Interfaces, 2022
Mehmet Sarikaya, Richard V Lee, Hadi Zareie   +2 more
exaly  

Nucleic Acid and Peptide Aptamers: Fundamentals and Bioanalytical Aspects

Angewandte Chemie - International Edition, 2012
Ilaria Palchetti, Sara Tombelli, Marco Mascini   +2 more
exaly  

Peptide nucleic acid: a versatile tool in genetic diagnostics and molecular biology

Current Opinion in Biotechnology, 2001
Peter E Nielsen
exaly