Affinity Purification of DNA and RNA from Environmental Samples with Peptide Nucleic Acid Clamps
Darrell P. Chandler+7 more
openalex +1 more source
Peptide Nucleic Acids and Biosensor Technology for Real-Time Detection of the Cystic Fibrosis W1282X Mutation by Surface Plasmon Resonance [PDF]
Giordana Feriotto+6 more
openalex +1 more source
This study develops a strategy to screen the active compounds from bio‐mixtures via combining transcriptomic profiling and molecular docking. The proposed method demonstrates 100% correction in three different biobased mixtures and is 3–20 times faster than traditional approaches.
Yongdong Xu+8 more
wiley +1 more source
Cell-Penetrating Peptide-Peptide Nucleic Acid Conjugates as a Tool for Protein Functional Elucidation in the Native Bacterium. [PDF]
Yokoi Y+6 more
europepmc +1 more source
Targeting peptide nucleic acid (PNA) oligomers to mitochondria within cells by conjugation to lipophilic cations: implications for mitochondrial DNA replication, expression and disease [PDF]
Aleksandra Muratovska+7 more
openalex +1 more source
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei+11 more
wiley +1 more source
Antiproliferative effect in chronic myeloid leukaemia cells by antisense peptide nucleic acids [PDF]
Valentina Rapozzi
openalex +1 more source
Based on the poor cartilage penetration of tFNA, a novel tFNA‐2WL with excellent cartilage permeability and perfect chondrocyte endocytosis properties is designed and fabricated. As a result, tFNA‐2WL has a nearly seven‐fold increase in the penetration depth into the cartilage, with the same excellent cell entry properties as tFNA.
Kui Huang+9 more
wiley +1 more source
De Novo Potent Peptide Nucleic Acid Antisense Oligomer Inhibitors Targeting SARS-CoV-2 RNA-Dependent RNA Polymerase via Structure-Guided Drug Design. [PDF]
Shehzadi K, Yu M, Liang J.
europepmc +1 more source