Results 201 to 210 of about 677,914 (356)

tRF‐5004b Enriched Secretory Autophagosomes Induce Endothelial Cell Activation to Drive Acute Respiratory Distress Syndrome

open access: yesAdvanced Science, EarlyView.
Acute respiratory distress syndrome (ARDS) is a severe lung condition with limited treatments, often triggered by overactive endothelial cells (ECs). It is identified that macrophage‐derived secretory autophagosomes (MSAPs) exacerbate lung damage by activating EC function.
Xing‐xing Zhu   +17 more
wiley   +1 more source

Influence of Different Cell-Penetrating Peptides on the Antimicrobial Efficiency of PNAs in Streptococcus pyogenes

open access: yesMolecular Therapy: Nucleic Acids, 2019
Streptococcus pyogenes is an exclusively human pathogen causing a wide range of clinical manifestations from mild superficial infections to severe, life-threatening, invasive diseases. S.
Gina Barkowsky   +7 more
doaj  

Randomized, Placebo-Controlled Trial of Product R, a Peptide-Nucleic Acid Immunomodulator, in the Treatment of Adults Infected with HIV [PDF]

open access: bronze, 2002
Levett Paul N.   +5 more
openalex   +1 more source

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti‐MicroRNA Therapies

open access: yesAdvances in Materials, 2016
K. R. Beavers   +10 more
semanticscholar   +1 more source

Cancer Specific CAIX‐Targeting Supramolecular Lysosome‐Targeting Chimeras (Supra‐LYTAC) for Targeted Protein Degradation

open access: yesAdvanced Science, EarlyView.
Spatiotemporal Supra‐LYTAC formation near cancerous membrane via CAIX‐targeting is achieved. As a result of generation of Supra‐LYTAC, POI trafficking into lysosome is significantly implemented for targeted protein degradation. Abstract Recently, targeted protein degradation (TPD) strategies have emerged as a promising solution to tackle undruggable ...
Dohyun Kim   +6 more
wiley   +1 more source

Peptide Nucleic Acids Containing Cationic/Amino-Alkyl Modified Bases Promote Enhanced Hybridization Kinetics and Thermodynamics with Single-Strand DNA. [PDF]

open access: yesACS Omega, 2023
Podlaski F   +9 more
europepmc   +1 more source

Peptide Nucleic Acid Probe Detection of Mutations in Mycobacterium tuberculosis Genes Associated with Drug Resistance [PDF]

open access: gold, 2002
Larry E. Bockstahler   +6 more
openalex   +1 more source

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