Results 201 to 210 of about 725,272 (355)

Characterization of iRGD-Ligand Modified Arginine-Histidine-Rich Peptides for Nucleic Acid Therapeutics Delivery to αvβ3 Integrin-Expressing Cancer Cells [PDF]

, 2020
Anna Egorova, Alexander Selutin, Marianna Maretina, S. А. Selkov, В. С. Баранов, Anton Kiselev   +5 more
openalex   +1 more source

TriCON: A Carbon‐Based Triple‐Modal Nanoplatform for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
We developed TriCON, a triple‐modality nanotherapeutic platform, to treat pancreatic ductal adenocarcinoma (PDAC) by synergizing gene editing, chemotherapy, and immunotherapy. TriCON utilizes CRISPR/Cas9 to target the poliovirus receptor (PVR), combined with nano‐encapsulated doxorubicin and checkpoint blockade. This approach achieved significant tumor
Xinyu Peng, Jiaxing Huang, Shengnan Lv, Jian Zhang, Liangliang Zhang, Huan Liu, Yan Liu, Zhen‐An Qiao, Feng Wei, Bao‐Lian Su   +9 more
wiley   +1 more source

Peptide Nucleic Acids Containing Cationic/Amino-Alkyl Modified Bases Promote Enhanced Hybridization Kinetics and Thermodynamics with Single-Strand DNA. [PDF]

ACS Omega, 2023
Podlaski F, Cornwell S, Wong K, McKittrick B, Kim JH, Jung D, Jeon Y, Jung KB, Tolias P, Windsor WT.   +9 more
europepmc   +1 more source

Rapid identification of Stenotrophomonas maltophilia by peptide nucleic acid fluorescence in situ hybridization

, 2014
Nana Wesley Hansen, Anders Rasmussen, Mark J. Fiandaca, Kasper Nørskov Kragh, Thomas Bjarnsholt, Niels Høiby, Henrik Stender, Luca Guardabassi   +7 more
openalex   +1 more source

Erratum: Tethered particle analysis of supercoiled circular DNA using peptide nucleic acid handles [PDF]

, 2014
Kamilla Nørregaard, Magnus Andersson, Peter E. Nielsen, Stanley Brown, Lene B. Oddershede   +4 more
openalex   +1 more source

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as Anti‐MicroRNA Therapies

Advances in Materials, 2016
K. R. Beavers, T. Werfel, Tianwei Shen, T. Kavanaugh, Kameron V. Kilchrist, J. Mares, Joshua S. Fain, Carrie B. Wiese, K. Vickers, S. Weiss, C. Duvall   +10 more
semanticscholar   +1 more source

Surface‐Associated Proteins on Extracellular Vesicles Remodel the Tumor Microenvironment by Potentiating TGF‐β Signaling in a Contact‐Dependent Manner

Advanced Science, EarlyView.
Extracellular vesicles (EVs) released from TGF‐β‐activated CAFs are enriched with ECM proteins such as TSG6 and THBS1, which facilitate their binding to recipient cell membranes. This EV–cell interaction promotes the clustering of CD44 and TGF‐β receptors on the target cell surface, thereby potentiating TGF‐β signaling activity. This study highlights a
Chao Li, Agustin Enciso‐Martinez, Lizhe Zhu, Sarah A. Rotman, Peter A. van Veelen, Roman I. Koning, Hailiang Mei, Peter ten Dijke   +7 more
wiley   +1 more source

Investigating the Interactions of Peptide Nucleic Acids with Multicomponent Peptide Hydrogels for the Advancement of Healthcare Technologies. [PDF]

Gels
Giordano S, Terracciano M, Gallo E, Diaferia C, Falanga AP, Accardo A, Franzese M, Salvatore M, Piccialli G, Borbone N, Oliviero G.   +10 more
europepmc   +1 more source

Antispacer peptide nucleic acids for sequence-specific CRISPR-Cas9 modulation. [PDF]

Nucleic Acids Res, 2022
Economos NG, Quijano E, Carufe KEW, Perera JDR, Glazer PM.   +4 more
europepmc   +1 more source

Cell-Penetrating Anti-Sense Peptide Nucleic Acids Targeting Sulfatase 2 Inhibit Adipogenesis in Human Mesenchymal Stem Cells

Daram Jung, Sungjin Ahn, Yeasel Jeon, Minhee Kim, In Guk Park, Areum Kim, Minsoo Noh   +6 more
openalex   +1 more source