Results 221 to 230 of about 677,914 (356)

Thyclotides, tetrahydrofuran-modified peptide nucleic acids that efficiently penetrate cells and inhibit microRNA-21. [PDF]

Nucleic Acids Res, 2022
Clausse V, Zheng H, Amarasekara H, Kruhlak M, Appella DH.   +4 more
europepmc   +1 more source

High‐Throughput Tiling of Essential mRNAs Increases Potency of Antisense Antibiotics

Advanced Science, EarlyView.
The systematic tiling of essential genes’ mRNA here presented, proposes a valuable tool for the identification of novel PNA sequences with antibiotic potential. The high‐throughput synthetic set up opens the door to investigating thousands of sequences in an economic way and ultimately identifies potent antisense oligonucleotides while also giving room
Giorgia Danti, Linda Popella, Jörg Vogel, Hans M. Maric   +3 more
wiley   +1 more source

Anti-Inflammatory Activity of Cell-Penetrating Peptide Nucleic Acids Targeting Indoleamine 2,3-Dioxygenase 1 in IFNγ-Treated Human Keratinocytes. [PDF]

Biomol Ther (Seoul)
Jung D, Ahn S, Park IG, Jeon Y, Lee S, Noh M.   +5 more
europepmc   +1 more source

Potentiating the Anti-Tuberculosis Efficacy of Peptide Nucleic Acids through Combinations with Permeabilizing Drugs. [PDF]

Microbiol Spectr, 2022
Cotta KB, Ghosh S, Mehra S.
europepmc   +1 more source

Peptide nucleic acids rather than RNA may have been the first genetic molecule

, 2000
Kevin E. Nelson, Matthew Levy, Stanley L. Miller   +2 more
openalex   +1 more source

Targeted delivery of DNA to the mitochondrial compartment via import sequence-conjugated peptide nucleic acid [PDF]

, 2003
Adrian Flierl, Christopher B. Jackson, Barbara A. Cottrell, Deborah G. Murdock, Peter Seibel, Douglas C. Wallace   +5 more
openalex   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

Detection of endothelin receptor subtypes mRNA in paraffin sections by in situ hybridization using peptide nucleic acid probes in human cirrhotic liver

, 2000
Hiroaki Yokomori, Masaya Oda, Yoshitaka Kamegaya, Nobuhiro Tsukada, Masahiko Nakamura, Hiromasa Ishii   +5 more
openalex   +1 more source

One-Step Detection of c-kit Point Mutations Using Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping and Hybridization Probes [PDF]

, 2003
Karl Sotlar, Luís Escribano, Olfert Landt, Stefanie Möhrle, Sonia Herrero, Antonio Torrelo, Ulrich Laß, Hans‐Peter Horny, B. Bültmann   +8 more
openalex   +1 more source

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

Advanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan, Ming Cai, Yiyu Wang, Hong‐Hui Wang, Zhou Nie   +4 more
wiley   +1 more source