359. Enhanced Gene Delivery by a Novel Tumor-Specific Vector Containing Peptide and Nucleic Acid Based Nuclear Translocation Signals [PDF]
Stanley Saamoah-Moffatt+2 more
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Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky+3 more
wiley +1 more source
Papain-Mediated Conjugation of Peptide Nucleic Acids to Delivery Peptides: A Density Functional Theory/Molecular Mechanics Metadynamics Study in Aqueous and Organic Solvent. [PDF]
González RD, Carvalho ATP.
europepmc +1 more source
Introduction of Peptide Functions into DNA by Nucleic Acid Peptides, NAPs [PDF]
Junji Kawakami+4 more
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Supramolecular Assembly of Triterpenoids: Current State and Biomedical Perspectives
Triterpenoids serve as both exceptional molecular motifs for supramolecular assembly and versatile therapeutic agents, offering broad biological functions to improve health outcomes and enhance treatment efficacy. This review comprehensively summarizes recent advances in triterpenoid‐based supramolecular systems, including their roles as functional ...
Jie Zhong+3 more
wiley +1 more source
Triplex-forming peptide nucleic acids as emerging ligands to modulate structure and function of complex RNAs. [PDF]
Katkevics M, MacKay JA, Rozners E.
europepmc +1 more source
The peptide nucleic acids (PNAs) as probes for chromosomal analysis of human oocytes and preimplantation embryos [PDF]
Franck Pellestor+5 more
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The Comprehensive Roadmap Toward Malaria Elimination Using Graphene and its Promising 2D Analogs
Material based on a diversity of graphene with chemical properties of strong strength, high mobility, high transparency, good heat conductivity, biocompatibility, and chemical stability, advanced devices demonstrating antimalarial characteristics can be used for malaria treatment at different stages of malaria development from the injection of ...
Fangzhou He+11 more
wiley +1 more source
Iron uptake pathway of Escherichia coli as an entry route for peptide nucleic acids conjugated with a siderophore mimic. [PDF]
Tsylents U+5 more
europepmc +1 more source