Results 261 to 270 of about 715,499 (306)
Aggregate, EarlyView.This study develops a supramolecular photosensitizer (SeVB⊃PQ) by combining SeVB with a P. gingivalis‐targeting peptide. SeVB⊃PQ selectively binds P. gingivalis, boosts ROS generation under irradiation, disrupts ATP synthesis, restores microbial balance, reduces inflammation, and promotes alveolar bone regeneration, offering a promising platform for ...
Rui Ding +7 more
wiley +1 more source
Triplex-Forming Peptide Nucleic Acids with Extended Backbones. [PDF]
Chembiochem, 2020 Kumar V, Brodyagin N, Rozners E.
europepmc +1 more source
Microgels for 3D Biofabrication
Aggregate, EarlyView.This review highlights microgels as a versatile platform advancing biomanufacturing and tissue regeneration. It details their fabrication methods, core functions (bioprinting inks, suspension support baths, porous sacrificial scaffolds), and pivotal applications (drug delivery, dynamic cell culture microenvironments, tissue engineering scaffolds ...
Ting Xie +11 more
wiley +1 more source
Aggregate, EarlyView.Mononuclear phagocytic cells with their natural ability to cross the blood brain barrier may provide new possibilities for glioma diagnosis and treatment. This review focused on mechanistic insights of the role of mononuclear phagocyte system (MPS) in central nerve system and glioma development, as well as the critical evaluation of development ...
Wenhui Wang +5 more
wiley +1 more source
Engineered RNA Devices for In Vivo Targeted Therapeutics via Advanced Delivery Systems
Aggregate, EarlyView.Schematic illustration of engineered RNA devices for in vivo targeted therapeutics via advanced delivery systems. ABSTRACT Engineered RNA devices can identify disease‐specific markers and precisely regulate gene expression, which is of great significance to the development of precision medicine.
Wei Luo +6 more
wiley +1 more source
Aggregate, EarlyView.This study addresses AMPs' clinical application challenges by enhancing stability via molecular assembly. Pba* shows high antibacterial activity, biocompatibility, and low toxicity, paving the way for antimicrobial materials. ABSTRACT Natural antimicrobial peptides (AMPs) encounter significant challenges in transitioning to clinical application ...
Xu Guo +7 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.This study integrates random matrix theory (RMT) and principal component analysis (PCA) to improve the identification of correlated regions in HIV protein sequences for vaccine design. PCA validation enhances the reliability of RMT‐derived correlations, particularly in small‐sample, high‐dimensional datasets, enabling more accurate detection of ...
Mariyam Siddiqah +3 more
wiley +1 more source