Results 21 to 30 of about 719,118 (354)

Peptide Nucleic Acids

Methods in Molecular Biology, 2020
P. Nielsen
semanticscholar   +3 more sources

In vivo interference of pea aphid endosymbiont Buchnera groEL gene by synthetic peptide nucleic acids. [PDF]

Sci Rep
Tan KXY, Shigenobu S.
europepmc   +3 more sources

Morphology and Applications of Self-Assembled Peptide Nucleic Acids. [PDF]

Int J Mol Sci
D'Andrea LD, Romanelli A.
europepmc   +2 more sources

Molecular Assembly of Triplex of Duplexes from Homothyminyl-Homocytosinyl Cγ(S/R)‑Bimodal Peptide Nucleic Acids with dA8/dG6 and the Cell Permeability of Bimodal Peptide Nucleic Acids [PDF]

ACS Omega, 2021
Pramod Bhingardeve, Prashant Jain, Krishna N. Ganesh   +2 more
doaj   +2 more sources

A minimal hybridization chain reaction (HCR) system using peptide nucleic acids

Chemical Science, 2021
The HCR represents a powerful tool for amplification in DNA-based circuitry and sensing applications, yet requires the use of long DNA sequences to grant hairpin metastability.
Ki Tae Kim, Simona Angerani, N. Winssinger   +2 more
semanticscholar   +1 more source

Conformational constraints of cyclopentane peptide nucleic acids facilitate tunable binding to DNA.

Nucleic Acids Research, 2021
We report a series of synthetic, nucleic acid mimics with highly customizable thermodynamic binding to DNA. Incorporation of helix-promoting cyclopentanes into peptide nucleic acids (PNAs) increases the melting temperatures (Tm) of PNA+DNA duplexes by ...
Hongchao Zheng, I. Botos, V. Clausse, Herman Nikolayevskiy, Elizabeth E. Rastede, Munira F. Fouz, S. Mazur, D. Appella   +7 more
semanticscholar   +1 more source

Artificial genetic polymers against human pathologies

Biology Direct, 2022
Originally discovered by Nielsen in 1991, peptide nucleic acids and other artificial genetic polymers have gained a lot of interest from the scientific community.
Gleb S. Ivanov, Vyacheslav G. Tribulovich, Nikolay B. Pestov, Temitope I. David, Abdul-Saleem Amoah, Tatyana V. Korneenko, Nikolai A. Barlev   +6 more
doaj   +1 more source

Sequence-Specific Recognition of Double-Stranded DNA by Peptide Nucleic Acid Forming Double-Duplex Invasion Complex

Applied Sciences, 2022
Peptide nucleic acid (PNA) is an analog of natural nucleic acids, where the sugar-phosphate backbone of DNA is replaced by an electrostatically neutral N-(2-aminoethyl)glycine backbone.
Yuichiro Aiba, Masanari Shibata, Osami Shoji   +2 more
doaj   +1 more source

Visible Light-Induced Templated Metathesis of Peptide–Nucleic Acid Conjugates with a Diselenide Bridge

Biomolecules, 2023
The use of template molecules as chemical scaffolds that significantly influence the course of the reaction has recently been intensively studied. Peptide nucleic acids (PNA) are molecules that mimic natural nucleic acids.
Mateusz Waliczek, Wiktoria Gancarz, Paulina Pochwała, Özge Pehlivan, Piotr Stefanowicz   +4 more
doaj   +1 more source

Papain-Mediated Conjugation of Peptide Nucleic Acids to Delivery Peptides: A Density Functional Theory/Molecular Mechanics Metadynamics Study in Aqueous and Organic Solvent. [PDF]

J Phys Chem B
González RD, Carvalho ATP.
europepmc   +2 more sources