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Peptide nucleic acids harness dual information codes in a single molecule.
Chemical Communications, 2020Nature encodes the information required for life in two fundamental biopolymers: nucleic acids and proteins. Peptide nucleic acid (PNA), a synthetic analog comprised of nucleobases arrayed along a pseudopeptide backbone, has the ability to combine the ...
Colin S. Swenson, J. Heemstra
semanticscholar +1 more source
ACS Nano, 2022
Strategies utilizing the CRISPR/Cas nucleases Cas13 and Cas12 have shown great promise in the development of highly sensitive and rapid diagnostic assays for the detection of pathogenic nucleic acids.
Christopher M. Green +5 more
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Strategies utilizing the CRISPR/Cas nucleases Cas13 and Cas12 have shown great promise in the development of highly sensitive and rapid diagnostic assays for the detection of pathogenic nucleic acids.
Christopher M. Green +5 more
semanticscholar +1 more source
Advances in Nanoparticle-based Delivery of Next Generation Peptide Nucleic Acids.
Current pharmaceutical design, 2019BACKGROUND Peptide nucleic acids (PNAs) belong to the next generation of synthetic nucleic acid analogues. Their high binding affinity and specificity towards the target DNA or RNA make them the reagent of choice for gene therapy-based applications ...
Shipra Malik +4 more
semanticscholar +1 more source
ACS Nano, 2021
Herein, we developed a photolabile spherical nucleic acid (PSNA) for carrier-free and near-infrared (NIR) photocontrolled self-delivery of small-interfering RNA (siRNA) and antisense oligonucleotide (ASO).
Lei Chen +4 more
semanticscholar +1 more source
Herein, we developed a photolabile spherical nucleic acid (PSNA) for carrier-free and near-infrared (NIR) photocontrolled self-delivery of small-interfering RNA (siRNA) and antisense oligonucleotide (ASO).
Lei Chen +4 more
semanticscholar +1 more source
Recent advances on application of peptide nucleic acids as a bioreceptor in biosensors development
Trends in Analytical Chemistry (TrAC), 2019Arezoo Saadati +6 more
semanticscholar +1 more source

