Results 1 to 10 of about 4,535,136 (383)

GibbsCluster: unsupervised clustering and alignment of peptide sequences [PDF]

Nucleic Acids Research, 2017
Receptor interactions with short linear peptide fragments (ligands) are at the base of many biological signaling processes. Conserved and information-rich amino acid patterns, commonly called sequence motifs, shape and regulate these interactions. Because of the properties of a receptor-ligand system or of the assay used to interrogate it, experimental
Massimo Andreatta, Bruno Alvarez, Morten Nielsen   +2 more
openaire   +8 more sources

Molecular evolution of a peptide GPCR ligand driven by artificial neural networks. [PDF]

PLoS ONE, 2012
Peptide ligands of G protein-coupled receptors constitute valuable natural lead structures for the development of highly selective drugs and high-affinity tools to probe ligand-receptor interaction.
Sebastian Bandholtz, Jörg Wichard, Ronald Kühne, Carsten Grötzinger   +3 more
doaj   +1 more source

BEBERAPA PENCIRI BERBASIS SEKUENS UNTUK MENGENALI SIFAT FUNGSIONAL PEPTIDA BIOAKTIF: STUDI EKSPLORASI

Jurnal Teknologi dan Industri Pangan, 2018
Bioactive peptides have important roles as functional food ingredients. The sequence patterns of amino acids in a peptide fragment may relate to their functional mechanisms.
Badrut Tamam, Dahrul Syah, Hanifah Nuryani Lioe, Maggy T. Suhartono, Wisnu Ananta Kusuma   +4 more
doaj   +1 more source

Separation of a set of peptide sequence isomers using differential ion mobility spectrometry.

Analytical Chemistry, 2011
Protein identification in bottom-up proteomics requires disentangling isomers of proteolytic peptides, a major class of which are sequence inversions. Their separation using ion mobility spectrometry (IMS) has been limited to isomeric pairs.
A. Shvartsburg, A. Creese, Richard D. Smith, H. Cooper   +3 more
semanticscholar   +1 more source

Purification of a human monocyte-derived neutrophil chemotactic factor that has peptide sequence similarity to other host defense cytokines.

Proceedings of the National Academy of Sciences of the United States of America, 1987
Stimulated human monocytes release several proteins thought to play a role in inflammation, including interleukin 1, tumor necrosis factor, and plasminogen activator.
T. Yoshimura, K. Matsushima, S. Tanaka, E. Robinson, E. Appella, J. Oppenheim, E. Leonard   +6 more
semanticscholar   +1 more source

QSYP Peptide Sequence Is Selected from Phage Display Libraries by Bovine IgG Contaminants in Monoclonal Antibody Preparations

BioTechniques, 2003
A consensus peptide sequence, QSYP, appears as an artifact during the mapping of monoclonal antibodies (MAbs) using a random peptide phage display library.
J.M. Jacobs, B.W. Bailey, J.B. Burritt, S.G. Morrison, R.P. Morrison, E.A. Dratz, A.J. Jesaitis, M. Teintze   +7 more
doaj   +1 more source

Polyproline-Rich Peptides Organize Four Cholinesterase Subunits into a Tetramer; BChE and AChE Scavenge Polyproline Peptides Released during Metabolic Turnover

Proceedings, 2020
The genes for acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) encode the proteins responsible for enzyme activity. Additional gene products, PRiMA and ColQ, anchor AChE and BChE proteins into membranes.
Oksana Lockridge, Lawrence M. Schopfer
doaj   +1 more source

Supramolecular Assembly of Peptide Amphiphiles

Accounts of Chemical Research, 2017
Conspectus Peptide amphiphiles (PAs) are small molecules that contain hydrophobic components covalently conjugated to peptides. In this Account, we describe recent advances involving PAs that consist of a short peptide sequence linked to an aliphatic ...
Mark P. Hendricks, Kohei Sato, Liam C. Palmer, S. Stupp   +3 more
semanticscholar   +1 more source

Mimotopes for alloreactive and conventional T cells in a peptide-MHC display library. [PDF]

PLoS Biology, 2004
The use of peptide libraries for the identification and characterization of T cell antigen peptide epitopes and mimotopes has been hampered by the need to form complexes between the peptides and an appropriate MHC molecule in order to construct a ...
Frances Crawford, Eric Huseby, Janice White, Philippa Marrack, John W Kappler   +4 more
doaj   +1 more source

Epitope Mapping of Streptococcus agalactiae Elongation Factor Tu Protein Recognized by Human Sera

Frontiers in Microbiology, 2018
The elongation factor Tu has been identified as one of the most immunoreactive proteins that was recognized by human sera of GBS (group B streptococcus) positive patients.
Marcelina Pyclik, Sabina Górska, Ewa Brzozowska, Anna Dobrut, Jarosław Ciekot, Andrzej Gamian, Monika Brzychczy-Włoch   +6 more
doaj   +1 more source