Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines. [PDF]
Sci Rep, 2019 Protein therapy holds great promise for treating a variety of diseases. To act on intracellular targets, therapeutic proteins must cross the plasma membrane.
Patel SG +9 more
europepmc +2 more sources
Mechanical characteristics of beta sheet-forming peptide hydrogels are dependent on peptide sequence, concentration and buffer composition. [PDF]
R Soc Open Sci, 2018 Self-assembling peptide hydrogels can be modified regarding their biodegradability, their chemical and mechanical properties and their nanofibrillar structure. Thus, self-assembling peptide hydrogels might be suitable scaffolds for regenerative therapies
Koch F +9 more
europepmc +2 more sources
Plastoglobule-Targeting Competence of a Putative Transit Peptide Sequence from Rice Phytoene Synthase 2 in Plastids. [PDF]
Int J Mol Sci, 2016 Plastoglobules (PGs) are thylakoid membrane microdomains within plastids that are known as specialized locations of carotenogenesis. Three rice phytoene synthase proteins (OsPSYs) involved in carotenoid biosynthesis have been identified.
You MK, Kim JH, Lee YJ, Jeong YS, Ha SH.
europepmc +2 more sources
Mapping membrane activity in undiscovered peptide sequence space using machine learning. [PDF]
Proc Natl Acad Sci U S A, 2016 Lee EY, Fulan BM, Wong GC, Ferguson AL.
europepmc +2 more sources
Data storage using peptide sequences [PDF]
Nature Communications, 2021 Abstract From the beginning of civilization, the media for storing data have been continuously evolving from such as stone tablets, animal bones and bamboo tablets to paper, with improvements on data density over time. Since the invention of electronics in the last century, the percentage of data stored in digital form has been increasing ...
Cheuk Chi A. Ng +7 more
openaire +6 more sources
Self-assembly of minimal peptoid sequences [PDF]
, 2020 Peptoids are biofunctional N-substituted glycine peptidomimics. Their self-assembly is of fundamental interest because they demonstrate alternatives to conventional peptide structures based on backbone chirality and beta-sheet hydrogen bonding.
Castelletto, Valeria +8 more
core +2 more sources
Ugi multicomponent reaction to prepare peptide–peptoid hybrid structures with diverse chemical functionalities [PDF]
, 2018 Monodisperse sequenced peptides and peptoids present unique nano-structures based on their self-assembled secondary and tertiary structures. However, the generation of peptide and peptoid hybrid oligomers in a sequence-defined manner via Ugi ...
Azevedo, Helena S. +12 more
core +1 more source
The Carboxyl-Terminal Segment of Apolipoprotein A-V Undergoes a Lipid-Induced Conformational Change [PDF]
, 2010 Apolipoprotein (apo) A-V is a 343-residue, multidomain protein that plays an important role in regulation of plasma triglyceride homeostasis. Primary sequence analysis revealed a unique tetraproline sequence (Pro293-Pro296) near the carboxyl terminus of ...
Lee, B. L. +4 more
core +2 more sources
Journal of the American Chemical Society, 2019 Just as peptide function is determined by the position, sequence, and overall arrangement of constituent amino acids, the optical proper-ties of nanoparticle (NP) assemblies are influenced by the size, dimensions, and arrangement of constituent NPs.
Soumitra Mokashi-Punekar +2 more
semanticscholar +1 more source
A Peptide Core Motif for Binding to Heterotrimeric G Protein α Subunits [PDF]
, 2005 Recently, in vitro selection using mRNA display was used to identify a novel peptide sequence that binds with high affinity to G{alpha}i1. The peptide was minimized to a 9-residue sequence (R6A-1) that retains high affinity and specificity for the GDP ...
Adhikari, Anirban +4 more
core +2 more sources