Results 111 to 120 of about 483,403 (312)
Development and Characterization of the Shortest Anti-Adhesion Peptide Analogue of B49Mod1
Molecules, 2020 Inhibition of cancer cell adhesion is an effective approach to killing adherent cancer cells. B49 and its analog B49Mod1 peptides, derived from the extracellular domain (ECD) of bone marrow stromal antigen 2 (BST-2), display anti-adhesion activity on ...
Yuan Lyu +2 more
doaj +1 more source
AMP0: Species-Specific Prediction of Anti-microbial Peptides using Zero and Few Shot Learning [PDF]
arXiv, 2019 The evolution of drug-resistant microbial species is one of the major challenges to global health. The development of new antimicrobial treatments such as antimicrobial peptides needs to be accelerated to combat this threat. However, the discovery of novel antimicrobial peptides is hampered by low-throughput biochemical assays. Computational techniques
arxiv
A gas-liquid solid phase peptide and protein sequenator [PDF]
, 1981 A new miniaturized protein and peptide sequenator has been constructed which uses gas phase reagents at the coupling and cleavage steps of the Edman degradation. The sample is embedded in a matrix of Polybrene dried onto a porous glass fiber disc located
Dreyer, William J. +3 more
core
Microscopic Mechanism of Specific Peptide Adhesion to Semiconductor Substrates
, 2010 The design of hybrid peptide-solid interfaces for nanotechnological applications such as biomolecular nanoarrays requires a deep understanding of the basic mechanisms of peptide binding and assembly at solid substrates.
+26 more
core +1 more source
MS²PIP: a tool for MS/MS peak intensity prediction [PDF]
, 2013 Motivation: Tandem mass spectrometry provides the means tomatch mass spectrometry signal observations with the chemical entities that generated them. The technology produces signal spectra that contain information about the chemical dissociation pattern ...
Degroeve, Sven, Martens, Lennart
core +2 more sources
Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression
Molecular Oncology, EarlyView.Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park +6 more
wiley +1 more source
Peptide Delivery to Tissues via Reversibly Linked Protein Transduction Sequences
BioTechniques, 2002 The development of peptide-based therapeutics has suffered from challenges associated with delivery to intact tissue. In skin, an array of protein targets resides only tens of micrometers below the surface; however, because of difficulties in traversing ...
P.B. Robbins +5 more
doaj +1 more source
Molecular Oncology, EarlyView.CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan +6 more
wiley +1 more source
Sumoylation silences the plasma membrane leak K+ channel K2P1. [PDF]
, 2005 Reversible, covalent modification with small ubiquitin-related modifier proteins (SUMOs) is known to mediate nuclear import/export and activity of transcription factors.
Butler, Margaret H +4 more
core +1 more source
Sequence rules for gold-binding peptides
RSC Advances, 2023 Classification based on association rules was applied to a dataset of decapeptides and their binding affinities for AuNPs. The sequence rules can accurately differentiate high-binding from low-binding affinity peptides.
openaire +2 more sources