Results 131 to 140 of about 1,077,842 (362)

Landscape of BRAF transcript variants in human cancer

Molecular Oncology, EarlyView.
We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda, Danilo Tatoni, Gianluca Mattei, Alberto Magi, Romina D'Aurizio, Laura Poliseno   +5 more
wiley   +1 more source

ESI-MS/MS Identification of a Bradykinin-Potentiating Peptide from Amazon Bothrops atrox Snake Venom Using a Hybrid Qq-oaTOF Mass Spectrometer

Toxins, 2013
A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m/z 1384.7386 was identified and characterized by collision induced dissociation (CID) using an ESI-MS/MS spectra obtained in positive ion mode on a hybrid Qq-oaTOF mass ...
Leonardo A. Calderon, Rodrigo G. Stábeli, Juliana P. Zuliani, Andreimar M. Soares, Anderson M. Kayano, Rodrigo S. Silva, Kayena D. Zaqueo, Gustavo H. M. F. Souza, Cleópatra A. S. Caldeira, Antonio Coutinho-Neto   +9 more
doaj   +1 more source

PepSim: T-cell cross-reactivity prediction via comparison of peptide sequence and peptide-HLA structure. [PDF]

Front Immunol, 2023
Hall-Swan S, Slone J, Rigo MM, Antunes DA, Lizée G, Kavraki LE.   +5 more
europepmc   +1 more source

The amino-acid sequence in the phenylalanyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates [PDF]

, 1951
Frederick Sanger, H. Tuppy
openalex   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Bitter peptide prediction using graph neural networks

Journal of Cheminformatics
Bitter taste is an unpleasant taste modality that affects food consumption. Bitter peptides are generated during enzymatic processes that produce functional, bioactive protein hydrolysates or during the aging process of fermented products such as cheese,
Prashant Srivastava, Alexandra Steuer, Francesco Ferri, Alessandro Nicoli, Kristian Schultz, Saptarshi Bej, Antonella Di Pizio, Olaf Wolkenhauer   +7 more
doaj   +1 more source

Reducing Peptide Sequence Bias in Quantitative Mass Spectrometry Data with Machine Learning. [PDF]

J Proteome Res, 2022
Dincer AB, Lu Y, Schweppe DK, Oh S, Noble WS.   +4 more
europepmc   +1 more source

Target-Specific De Novo Peptide Binder Design with DiffPepBuilder [PDF]

arXiv
Despite the exciting progress in target-specific de novo protein binder design, peptide binder design remains challenging due to the flexibility of peptide structures and the scarcity of protein-peptide complex structure data. In this study, we curated a large synthetic dataset, referred to as PepPC-F, from the abundant protein-protein interface data ...
arxiv  

A 2D IR Study of Isotope-Edited Variants of the Elastin-like GVGVPGVG Peptide and the Size Dependent Behavior of (VPGVG)n [PDF]

arXiv, 2017
This study uses two-dimensional infrared (2D IR) spectroscopy in conjunction with isotope labeling and spectral modeling from molecular dynamics simulations to identify the dominant turn conformations that exist in equilibrium ensembles of the (VPGVG)n family of intrinsically disordered elastin-like peptides.
arxiv  

Amino acid sequence in lysozyme. 2. Elution chromatography of peptides on ion-exchange resins [PDF]

, 1955
Adrienne R. Thompson
openalex   +1 more source