Results 141 to 150 of about 1,077,842 (362)

Helix vs. Sheet Formation in a Small Peptide

, 2003
Segments with the amino acid sequence EKAYLRT appear in natural occurring proteins both in $\alpha$-helices and $\beta$-sheets. For this reason, we have use this peptide to study how secondary structure formation in proteins depends on the local ...
A. Wind, A.M. Ferrenberg, A.M. Ferrenberg, B.A. Berg, D.L. Minor, Jr., F. Eisenmenger, G. Némethy, J.Z.Y. Chen, N.A. Alves, N.A. Alves, S. Sudarsanam, T. Ooi, U.H.E. Hansmann, U.H.E. Hansmann, U.H.E. Hansmann, Ulrich H. E. Hansmann, Y. Okamoto, Y. Peng, Y. Peng, Yong Peng   +19 more
core   +1 more source

MASS SPECTROMETRIC SEQUENCING OF PEPTIDES AND PROTEINS [PDF]

Pure and Applied Chemistry, 1978
Mass spectrometry had been demonstrated to be a useful technique for the determination of the amino acid sequence in oligopeptides. The extension to the sequencing of polypeptides and proteins is a complex problem involving chemical degradation and conversion techniques, separations, collection of the mass spectral information and the interpretation ...
openaire   +2 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

Peptide Utility (PU) search server: A new tool for peptide sequence search from multiple databases. [PDF]

Heliyon, 2022
Chamoli T, Khera A, Sharma A, Gupta A, Garg S, Mamgain K, Bansal A, Verma S, Gupta A, Alajangi HK, Singh G, Barnwal RP.   +11 more
europepmc   +1 more source

Studies on the determination of the sequence of amino acids in peptides and proteins. 4. The synthesis of 3-(4′-dimethylamino-3′:5′-dinitrophenyl)-2-thiohydantoin derivatives of various amino acids, and their use for amino acid-sequence determinations [PDF]

, 1954
W Reith, Norman M. Waldron
openalex   +1 more source

On subcellular distribution of the zinc finger 469 protein (ZNF469) and observed discrepancy in the localization of endogenous and overexpressed ZNF469

FEBS Open Bio, EarlyView.
ZNF469 regulates the expression of genes encoding extracellular matrix proteins. Endogenous ZNF469 is predominantly cytoplasmic, while in transfected cells, it forms aggregates reminiscent of biomolecular condensates, located mainly in the nucleus. These condensates exhibit overlapping staining with proteasomes and are also associated with the mitotic ...
Anne Elisabeth Christensen Mellgren, Ileana Cristea, Thomas Stevenson, Endy Spriet, Per Morten Knappskog, Stig Ove Bøe, Harald Kranz, Sushma N. Grellscheid, Eyvind Rødahl   +8 more
wiley   +1 more source

The amino-acid sequence in the glycyl chain of insulin. 2. The investigation of peptides from enzymic hydrolysates [PDF]

, 1953
Frederick Sanger, E.O.P. Thompson
openalex   +1 more source

Targeted delivery of anti-inflammatory therapy to rheumatoid tissue by fusion proteins containing an IL-4-linked synovial targeting peptide [PDF]

, 2011
We provide first-time evidence that the synovial endothelium-targeting peptide (SyETP) CKSTHDRLC successfully delivers conjugated IL-4 to human rheumatoid synovium transplanted into SCID mice. SyETP, previously isolated by in vivo phage display and shown
Ahuva Nissim, Ciara M. Finucane, Costantino Pitzalis, Danielle DiCara, Michele Bombardieri, Rita Jones, Sarah E. Wythe, Stephen J. Mather, Taher E. I. Taher, Y. K. Stella Man, Yuti Chernajovsky   +10 more
core   +1 more source

Protein O‐glycosylation in the Bacteroidota phylum

FEBS Open Bio, EarlyView.
Species of the Bacteroidota phylum exhibit a unique O‐glycosylation system. It modifies noncytoplasmic proteins on a specific amino acid motif with a shared glycan core but a species‐specific outer glycan. A locus of multiple glycosyltransferases responsible for the synthesis of the outer glycan has been identified.
Lonneke Hoffmanns, Dennis Svedberg, André Mateus   +2 more
wiley   +1 more source

Peptide Sequence of Pili Subunit Protein 49.8 kDa Shigella flexneri as Antigenic Epitope for Shigellosis Vaccine Development. [PDF]

Turk J Pharm Sci, 2022
Anam K, Endharti AT, Poeranto S, Prawiro SR.   +3 more
europepmc   +1 more source