Results 151 to 160 of about 4,591,646 (406)

Antihyperuricemic activity and inhibition mechanism of xanthine oxidase inhibitory peptides derived from whey protein by virtual screening

open access: yesJournal of Dairy Science
: Xanthine oxidase (XO), a rate-limiting enzyme in uric acid production, is the pivotal therapeutic target for gout and hyperuricemia. In this study, 57 peptides from α-lactalbumin and β-lactoglobulin were obtained via virtual enzymatic hydrolysis, and ...
Yaru Xu, Han Gong, Yang Zou, Xueying Mao
doaj  

ESI-MS/MS Identification of a Bradykinin-Potentiating Peptide from Amazon Bothrops atrox Snake Venom Using a Hybrid Qq-oaTOF Mass Spectrometer

open access: yesToxins, 2013
A bradykinin-potentiating peptide (BPP) from Amazon Bothrops atrox venom with m/z 1384.7386 was identified and characterized by collision induced dissociation (CID) using an ESI-MS/MS spectra obtained in positive ion mode on a hybrid Qq-oaTOF mass ...
Leonardo A. Calderon   +9 more
doaj   +1 more source

PEPMatch: a tool to identify short peptide sequence matches in large sets of proteins. [PDF]

open access: yesBMC Bioinformatics, 2023
Marrama D   +8 more
europepmc   +1 more source

ACPred-FL: a sequence-based predictor using effective feature representation to improve the prediction of anti-cancer peptides

open access: yesBioinform., 2018
Motivation Anti-cancer peptides (ACPs) have recently emerged as promising therapeutic agents for cancer treatment. Due to the avalanche of protein sequence data in the post-genomic era, there is an urgent need to develop automated computational methods ...
Leyi Wei   +4 more
semanticscholar   +1 more source

Protein Sequencing with an Adaptive Genetic Algorithm from Tandem Mass Spectrometry

open access: yes, 2008
In Proteomics, only the de novo peptide sequencing approach allows a partial amino acid sequence of a peptide to be found from a MS/MS spectrum. In this article a preliminary work is presented to discover a complete protein sequence from spectral data ...
Boisson, Jean-Charles   +3 more
core   +2 more sources

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

A 2D IR Study of Isotope-Edited Variants of the Elastin-like GVGVPGVG Peptide and the Size Dependent Behavior of (VPGVG)n [PDF]

open access: yesarXiv, 2017
This study uses two-dimensional infrared (2D IR) spectroscopy in conjunction with isotope labeling and spectral modeling from molecular dynamics simulations to identify the dominant turn conformations that exist in equilibrium ensembles of the (VPGVG)n family of intrinsically disordered elastin-like peptides.
arxiv  

Impact of Peptide Sequence on Functional siRNA Delivery and Gene Knockdown with Cyclic Amphipathic Peptide Delivery Agents. [PDF]

open access: yesMol Pharm, 2023
Jagrosse ML   +8 more
europepmc   +1 more source

Peptide sequence and conformation strongly influence tryptophan fluorescence.

open access: yesBiophysical Journal, 2008
This article probes the denatured state ensemble of ribonuclease Sa (RNase Sa) using fluorescence. To interpret the results obtained with RNase Sa, it is essential that we gain a better understanding of the fluorescence properties of tryptophan (Trp) in ...
R. W. Alston   +5 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy